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PSMC2 Gene Record

  • Summary
  • Interactions
  • Claims
  • PSMC2 5701

    Alternate Names:

    5701
    PROTEASOME 26S SUBUNIT, ATPASE 2
    PSMC2
    MSS1
    Nbla10058
    S7
    154365
    9548
    ENSG00000161057
    OTTHUMG00000157206
    Protein MSS1
    Proteasome 26S subunit ATPase 2
    26S proteasome AAA-ATPase subunit RPT1
    26S protease regulatory subunit 7
    Proteasome
    RPT1
    P35998
    26S proteasome regulatory subunit 7

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    PROTEASE
    TRANSCRIPTION FACTOR

    Publications:

    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem
  • CARFILZOMIB   PSMC2

    Interaction Score: 1.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • BORTEZOMIB   PSMC2

    Interaction Score: 0.69

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    24524217


    Sources:
    DTC MyCancerGenome ChemblInteractions

  • IXAZOMIB CITRATE   PSMC2

    Interaction Score: 0.41

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction 26S proteosome inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • OPROZOMIB   PSMC2

    Interaction Score: 0.4

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction 26S proteosome inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000161057

    • Version: 101_38

    Alternate Names:
    PSMC2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DTC: PSMC2

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Kawamura S et al., 2014, Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates., J Med Chem

  • MyCancerGenome: PSMC2

    • Version: 20-Jun-2017

    Alternate Names:
    5701 Entrez Gene Id
    PSMC2 MyCancerGenome Gene Symbol
    Proteasome MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • ChemblInteractions: MSS1

    • Version: chembl_23

    Alternate Names:
    MSS1 GENE_SYMBOL
    PSMC2 GENE_SYMBOL
    26S protease regulatory subunit 7 UNIPROT

    Gene Info:

    Publications:

  • dGene: PSMC2

    • Version: 27-Jun-2013

    Alternate Names:
    5701 Gene ID
    MSS1 dGene Synonym
    Nbla10058 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • Pharos: PSMC2

    • Version: 01-February-2022

    Alternate Names:
    26S proteasome regulatory subunit 7 Gene Name
    P35998 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21