• Interaction Score: 14.18

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Direct Interaction? True

  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Trial Name AM-211

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Membrane binding assay using human DP2 stably expressed in K562 leukemia cells.
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Details of the Assay for Interaction Displacement of [<sup>3</sup>H]PGD<sub>2</sub> from human DP<sub>2</sub> receptor

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 7.09

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 7.09

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 3.54

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.54

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes
    Specific Action of the Ligand Antagonist

    PMIDs:
    None found


  • Interaction Score: 2.13

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    16256979


  • Interaction Score: 1.77

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction G protein-coupled receptor 44 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.55

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    PMIDs:
    9579725


  • Interaction Score: 0.51

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.39

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction G protein-coupled receptor 44 antagonist

    PMIDs:
    None found


  • Interaction Score: 0.37

    Interaction Types & Directionality:
    agonist (activating)
    other/unknown

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Full agonist

    • Version: 101_38

    Alternate Names:
    PTGDR2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    GPR44 Display Id
    ENSG00000183134 Ensembl Gene Id
    PUTATIVE G-PROTEIN COUPLED RECEPTOR 44 (CHEMOATTRACTANT RECEPTOR- HOMOLOGOUS MOLECULE EXPRESSED ON TH2 CELLS). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y5Y4] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    PD2R2_HUMAN Uniprot Id
    PTGDR2 Uniprot Gene Name
    Q9Y5Y4 Uniprot Accession

    Gene Info:
    Interpro Type Family
    Interpro Name GPCR, rhodopsin-like, 7TM
    Interpro Short Name 7TM_GPCR_Rhodpsn

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

    • Version: January-2014

    Alternate Names:
    GPR44 Gene Symbol
    PD2R2 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass GPCR
    Target Subclass Rhodopsin

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    4502 HUGO Gene ID
    4502 HUGO Gene Symbol
    prostaglandin D2 receptor 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Prostanoid receptors
    GuideToPharmacology Gene Category ID 58

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000183134 Gene Symbol
    PTGDR2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    DL1R GENE_SYMBOL
    GPR44 GENE_SYMBOL
    PTGDR2 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    11251 Gene ID
    CD294 dGene Synonym
    CRTH2 dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    PTGDR2 TTD Gene Abbreviation
    T61722 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    CRTH2 GO Gene Synonym
    DL1R GO Gene Synonym
    GPR44 GO Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Prostaglandin D2 receptor 2 Gene Name
    Q9Y5Y4 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: