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RARG 5916 Druggable Genome
Alternate Names:
5916 RETINOIC ACID RECEPTOR GAMMA RARG NR1B3 RARC 180190 9866 ENSG00000172819 OTTHUMG00000048077 P13631 RARG_HUMAN 592 NP_000957|NP_001036193 NM_001042728 Retinoic acid receptor-γ RETINOIC ACID RECEPTOR GAMMA-2 (RAR-GAMMA-2). [SOURCE:UNIPROT/SWISSPROT;ACC:P22932] RAR-gamma Nuclear receptor subfamily 1 group B member 3 PA34227 T82146 Gene Info:
Human Readable Name NUCLEAR HORMONE RECEPTOR Interpro Name Nuclear hormone receptor, ligand-binding, core Human Readable Name DRUGGABLE GENOME Interpro Acc IPR000536 Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Short Name Nucl_hrmn_rcpt_lig-bd_core Interpro Type Domain GuideToPharmacology Gene Category Name 1B. Retinoic acid receptors GuideToPharmacology Gene Category ID 85 Target Class Receptors Target Subclass Nuclear receptor Initial Gene Query NR1B3 Counted Citations from 1950-2000 597 Target Main Class Receptors Gene Biotype PROTEIN_CODING Gene Categories: Category Details
TRANSCRIPTION FACTOR COMPLEX NUCLEAR HORMONE RECEPTOR DRUGGABLE GENOME Publications:
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Interaction Score: 11.26
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction? True Endogenous Drug? False Specific Action of the Ligand Agonist -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Retinoic acid receptor agonist Direct Interaction yes Trial Name - -
Interaction Score: 4.69
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name tazarotene,Tazorac Novel drug target Established target Specific Action of the Ligand Agonist
-
Interaction Score: 3.75
-
Interaction Score: 3.75
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Agonist Endogenous Drug? False Direct Interaction? True
Sources:
ChemblInteractions TEND GuideToPharmacology TTD -
Interaction Score: 3.75
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Details of the Assay for Interaction Ligand-induced activation in a cellular reporter assay utlising the RARγ receptor ligand-binding domain. Specific Action of the Ligand Agonist Endogenous Drug? False -
Interaction Score: 2.14
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Retinoid receptor agonist Direct Interaction yes -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Retinoic acid receptor agonist Direct Interaction yes Trial Name tretinoin microsponge,Retin-A -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Retinoic acid receptor antagonist Direct Interaction yes -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Retinoid receptor agonist Direct Interaction yes -
Interaction Score: 0.94
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Agonist -
Interaction Score: 0.68
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Retinoic acid receptor agonist Direct Interaction yes -
Interaction Score: 0.63
Interaction Types & Directionality:
modulator Interaction Info:
Direct Interaction yes Mechanism of Interaction Retinoid receptor modulator -
Interaction Score: 0.54
-
Interaction Score: 0.14
Interaction Types & Directionality:
n/a Interaction Info:
Novel drug target Established target Trial Name fenretinide, RT-101 -
Interaction Score: 0.06
-
Interaction Score: 0.04
-
- Version: 101_38
Alternate Names:
RARG Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
Alternate Names:
5916 Entrez Gene Id RARG_HUMAN Uniprot Id P13631 Uniprot Accession Gene Info:
Target Subclass Nuclear receptor Target Main Class Receptors Publications:
-
- Version: 11-September-2012
Alternate Names:
5916 Entrez Gene Id RARG_HUMAN Uniprot Id RETINOIC ACID RECEPTOR GAMMA Uniprot Protein Name Gene Info:
Interpro Name Nuclear hormone receptor, ligand-binding, core Human Readable Name DRUGGABLE GENOME Interpro Acc IPR000536 Gene Categories:
NUCLEAR HORMONE RECEPTOR, DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
RETINOIC ACID RECEPTOR GAMMA-2 (RAR-GAMMA-2). [SOURCE:UNIPROT/SWISSPROT;ACC:P22932] Description ENSG00000172819 Ensembl Gene Id RARG Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: January-2014
Alternate Names:
RARG Gene Symbol Gene Info:
Target Class Receptors Target Subclass Nuclear receptor Publications:
-
- Version: February-2014
Alternate Names:
5916 Entrez Gene ID Gene Info:
Initial Gene Query NR1B3 Counted Citations from 1950-2000 597 Gene Categories:
NUCLEAR HORMONE RECEPTOR Publications:
-
- Version: 29-September-2020
Alternate Names:
9866 HUGO Gene ID 9866 HUGO Gene Symbol retinoic acid receptor gamma HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name 1B. Retinoic acid receptors GuideToPharmacology Gene Category ID 85 Gene Categories:
NUCLEAR HORMONE RECEPTOR Publications:
-
Alternate Names:
Gene Info:
Publications:
-
Alternate Names:
Gene Info:
Publications:
-
- Version: 31-May-2017
Alternate Names:
ENSG00000172819 Gene Symbol RARG Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
- Version: chembl_23
Alternate Names:
NR1B3 GENE_SYMBOL RARG GENE_SYMBOL Retinoic acid receptor gamma UNIPROT Gene Info:
Publications:
-
Alternate Names:
PA34227 PharmGKB ID Gene Info:
Publications:
-
Alternate Names:
5916 Gene ID NR1B3 dGene Synonym RARC dGene Synonym Gene Info:
Gene Categories:
NUCLEAR HORMONE RECEPTOR Publications:
-
- Version: 2020.06.01
Alternate Names:
RARG TTD Gene Abbreviation T82146 TTD Target ID Gene Info:
Publications:
-
Alternate Names:
NR1B3 GO Gene Synonym Gene Info:
Gene Categories:
TRANSCRIPTION FACTOR COMPLEX, NUCLEAR HORMONE RECEPTOR Publications: