• RXFP2 122042 Druggable Genome

    Alternate Names:

    122042
    RELAXIN/INSULIN LIKE FAMILY PEPTIDE RECEPTOR 2
    RXFP2
    GPR106
    GREAT
    INSL3R
    LGR8
    LGR8.1
    RXFPR2
    606655
    17318
    ENSG00000133105
    OTTHUMG00000016690
    Q8WXD0
    RXFP2_HUMAN
    RELAXIN RECEPTOR 2
    RELAXIN RECEPTOR 2 (LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 8) (G-PROTEIN COUPLED RECEPTOR AFFECTING TESTICULAR DESCENT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8WXD0]
    352
    G-protein coupled receptor 106
    G-protein coupled receptor affecting testicular descent
    Leucine-rich repeat-containing G-protein coupled receptor 8
    Relaxin family peptide receptor 2
    NP_570718
    NM_130806

    Gene Info:

    Interpro Acc IPR000276
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Interpro Name GPCR, rhodopsin-like, 7TM
    Uniprot Status Swiss-Prot
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name Relaxin family peptide receptors
    GuideToPharmacology Gene Category ID 60
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 4.56

    Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Mechanism of Interaction Relaxin receptor 2 activator
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 3.04

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Endogenous Drug? False
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    PMIDs:
    None found


  • Interaction Score: 1.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.83

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    RXFP2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    RXFP2 Uniprot Gene Name
    RXFP2_HUMAN Uniprot Id
    RELAXIN RECEPTOR 2 Uniprot Protein Name

    Gene Info:
    Interpro Acc IPR000276
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    RELAXIN RECEPTOR 2 (LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 8) (G-PROTEIN COUPLED RECEPTOR AFFECTING TESTICULAR DESCENT). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8WXD0] Description
    LGR8 Display Id
    ENSG00000133105 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    17318 HUGO Gene ID
    17318 HUGO Gene Symbol
    relaxin family peptide receptor 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Relaxin family peptide receptors
    GuideToPharmacology Gene Category ID 60

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000133105 Gene Symbol
    RXFP2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    GREAT GENE_SYMBOL
    LGR8 GENE_SYMBOL
    RXFP2 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    Q8WXD0 UniProt ID
    ENSG00000133105 Ensembl Gene ID
    GPR106 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    122042 Gene ID
    GPR106 dGene Synonym
    GREAT dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Relaxin receptor 2 Gene Name
    Q8WXD0 UniProt ID

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: