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SAG Gene Record

  • Summary
  • Interactions
  • Claims
  • SAG 6295

    Alternate Names:

    6295
    S-ANTIGEN VISUAL ARRESTIN
    SAG
    RP47
    S-AG
    181031
    10521
    ENSG00000130561
    OTTHUMG00000153213
    P10523

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Enzyme regulator
    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Palestine et al., 1987, Bromocriptine and low dose cyclosporine in the treatment of experimental autoimmune uveitis in the rat., J. Clin. Invest.
    Chan et al., 1987, Cyclosporine and dexamethasone inhibit T-lymphocyte MHC class II antigens and IL-2 receptor expression in experimental autoimmune uveitis., Immunol. Invest.
    Jaramillo et al., 1992, Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation., Curr. Eye Res.
  • PEPTIDE B27PD   SAG

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name B27PD,Optiquel
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • BROMOCRIPTINE   SAG

    Interaction Score: 1.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3494043


    Sources:
    NCI

  • INDOMETHACIN   SAG

    Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1324133


    Sources:
    NCI

  • CYCLOSPORINE   SAG

    Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3123380


    Sources:
    NCI

  • DEXAMETHASONE   SAG

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3123380


    Sources:
    NCI

  • Ensembl: ENSG00000130561

    • Version: 101_38

    Alternate Names:
    SAG Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P10523

    • Version: January-2014

    Alternate Names:
    SAG Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Enzyme regulator

    Publications:

  • NCI: SAG

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Jaramillo et al., 1992, Modulation of immune responses by cyclo-oxygenase inhibitors during intraocular inflammation., Curr. Eye Res.
    Chan et al., 1987, Cyclosporine and dexamethasone inhibit T-lymphocyte MHC class II antigens and IL-2 receptor expression in experimental autoimmune uveitis., Immunol. Invest.
    Ni et al., 1990, FR900506 (FK506) and 15-deoxyspergualin (15-DSG) modulate the kinetics of infiltrating cells in eyes with experimental autoimmune uveoretinitis., Autoimmunity

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21