6323 |
SODIUM VOLTAGE-GATED CHANNEL ALPHA SUBUNIT 1 |
SCN1A |
EIEE6 |
FEB3 |
FEB3A |
FHM3 |
GEFSP2 |
HBSCI |
NAC1 |
Nav1.1 |
SCN1 |
SMEI |
182389 |
10585 |
ENSG00000144285 |
OTTHUMG00000044173 |
SCN1A_HUMAN |
P35498 |
Sodium channel protein brain I subunit alpha |
Voltage-gated sodium channel subunit alpha Nav1.1 |
Sodium channel protein type I subunit alpha |
Sodium channel protein type 1 subunit alpha |
PA301 |
SODIUM CHANNEL PROTEIN TYPE I ALPHA SUBUNIT (VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNIT NAV1.1) (SODIUM CHANNEL PROTEIN, BRAIN I ALPHA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P35498] |
DEE6 |
DRVT |
DEE6A |
DEE6B |
Initial Gene Query | Nav1.1 |
Counted Citations from 1950-2000 | 398 |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.7 |
Interpro Short Name | Ion_trans_dom |
Interpro Acc | IPR005821 |
Human Readable Name | ION CHANNEL |
Uniprot Evidence | 1: Evidence at protein level |
Human Readable Name | DRUGGABLE GENOME |
Uniprot Status | Swiss-Prot |
Interpro Type | Domain |
Interpro Name | Ion transport domain |
Target Subclass | Voltage_gated_ion_channels |
Target Main Class | Transporters |
Target Subclass | Channels |
Transmembrane Helix Count | 24 |
Target Subclass | SodiumChannels |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
blocker (inhibitory) |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | zonisamide,Zonegran, Trerief |
Trial Name | OREX-003, olanzapine plus zonisamide SR |
Novel drug target | Established target |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Novel drug target | Established target |
Trial Name | tetrodotoxin,Tectin, Tetrodin |
blocker (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
Trial Name | topiramate controlled release,Trokesa |
blocker (inhibitory) |
inhibitor (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
other/unknown |
Trial Name | - |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
n/a |
Trial Name | Safinamide |
Novel drug target | Established target |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
blocker (inhibitory) |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
Direct Interaction | yes |
blocker (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Sodium channel alpha subunit blocker |
SCN1A | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
SCN1A | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:1.A.1.10.7 |
SCN1A | Gene Symbol |
SCN1A_HUMAN | Uniprot Id |
ENSG00000144285 | Ensembl Gene Id |
Target Subclass | Voltage_gated_ion_channels |
Target Main Class | Transporters |
Target Subclass | Channels |
SODIUM CHANNEL PROTEIN TYPE I ALPHA SUBUNIT (VOLTAGE-GATED SODIUM CHANNEL ALPHA SUBUNIT NAV1.1) (SODIUM CHANNEL PROTEIN, BRAIN I ALPHA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P35498] | Description |
ENSG00000144285 | Ensembl Gene Id |
SCN1A | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
6323 | Entrez Gene ID |
Initial Gene Query | Nav1.1 |
Counted Citations from 1950-2000 | 398 |
ION CHANNEL |
SCN1A | Uniprot Gene Name |
SCN1A_HUMAN | Uniprot Id |
ENSG00000144285 | Ensembl Gene Id |
Interpro Short Name | Ion_trans_dom |
Interpro Acc | IPR005821 |
Human Readable Name | ION CHANNEL |
ION CHANNEL, DRUGGABLE GENOME |
PA301 | PharmGKB ID |
ENSG00000144285 | Gene Symbol |
SCN1A | Ensembl Id |
DRUGGABLE GENOME |
SCN1 | GENE_SYMBOL |
SCN1A | GENE_SYMBOL |
Sodium channel protein type 1 subunit alpha | UNIPROT |
Sodium channel protein type 1 subunit alpha | Gene Name |
P35498 | UniProt ID |
ION CHANNEL |