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SCNN1B 6338 Druggable Genome
Alternate Names:
6338 SODIUM CHANNEL EPITHELIAL 1 BETA SUBUNIT SCNN1B BESC1 ENaCb ENaCbeta SCNEB 600760 10600 ENSG00000168447 OTTHUMG00000131608 P51168 SCNNB_HUMAN AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA Nonvoltage-gated sodium channel 1 subunit beta Beta-ENaC Epithelial Na(+) channel subunit beta Beta-NaCH PA306 AMILORIDE-SENSITIVE SODIUM CHANNEL BETA-SUBUNIT (EPITHELIAL NA+ CHANNEL BETA SUBUNIT) (BETA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 BETA SUBUNIT) (SCNEB) (BETA NACH) (ENACB). [SOURCE:UNIPROT/SWISSPROT;ACC:P51168] SODIUM CHANNEL EPITHELIAL 1 SUBUNIT BETA LIDLS1 Gene Info:
Uniprot Status Swiss-Prot Interpro Type Family Interpro Short Name Na+channel_ASC Interpro Acc IPR001873 Human Readable Name DRUGGABLE GENOME Uniprot Evidence 1: Evidence at protein level Human Readable Name ION CHANNEL Interpro Name Na+ channel, amiloride-sensitive Transmembrane Helix Count 2 Target Subclass Amiloride-sensitive Na+ channel Target Subclass Channels Target Main Class Transporters Target Class Transporters Target Subclass TC:1.A.6.1.1 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL EXTERNAL SIDE OF PLASMA MEMBRANE DRUGGABLE GENOME Publications:
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Interaction Score: 10.3
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Interaction Score: 5.15
Interaction Types & Directionality:
blocker (inhibitory) inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name - Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker
Sources:
TdgClinicalTrial ChemblInteractions TEND PharmGKB -
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Direct Interaction yes -
Interaction Score: 2.58
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Mechanism of Interaction Amiloride-sensitive sodium channel, ENaC blocker Direct Interaction yes
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- Version: 101_38
Alternate Names:
SCNN1B Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000168447 Ensembl Gene Id SCNN1B Display Id AMILORIDE-SENSITIVE SODIUM CHANNEL BETA-SUBUNIT (EPITHELIAL NA+ CHANNEL BETA SUBUNIT) (BETA ENAC) (NONVOLTAGE-GATED SODIUM CHANNEL 1 BETA SUBUNIT) (SCNEB) (BETA NACH) (ENACB). [SOURCE:UNIPROT/SWISSPROT;ACC:P51168] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
SCNN1B Gene Symbol Gene Info:
Target Class Transporters Target Subclass TC:1.A.6.1.1 Publications:
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Alternate Names:
6338 Entrez Gene Id SCNNB_HUMAN Uniprot Id ENSG00000168447 Ensembl Gene Id Gene Info:
Transmembrane Helix Count 2 Target Subclass Amiloride-sensitive Na+ channel Target Subclass Channels Publications:
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- Version: 11-September-2012
Alternate Names:
6338 Entrez Gene Id AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA Uniprot Protein Name SCNN1B Uniprot Gene Name Gene Info:
Uniprot Status Swiss-Prot Interpro Type Family Interpro Short Name Na+channel_ASC Gene Categories:
ION CHANNEL, DRUGGABLE GENOME Publications:
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Alternate Names:
PA306 PharmGKB ID Gene Info:
Publications:
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- Version: chembl_23
Alternate Names:
SCNN1B GENE_SYMBOL Amiloride-sensitive sodium channel subunit beta UNIPROT Beta-NaCH UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000168447 Gene Symbol SCNN1B Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
Amiloride-sensitive sodium channel subunit beta Gene Name P51168 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications:
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Alternate Names:
Gene Info:
Gene Categories:
EXTERNAL SIDE OF PLASMA MEMBRANE Publications: