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SLC28A3 Gene Record

  • Summary
  • Interactions
  • Claims
  • SLC28A3 64078 Druggable Genome

    Alternate Names:

    64078
    SOLUTE CARRIER FAMILY 28 MEMBER 3
    SLC28A3
    CNT3
    608269
    16484
    ENSG00000197506
    OTTHUMG00000020117
    PA426
    Q9HAS3

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

    Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos
    Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
    Alvarellos ML et al., 2014, PharmGKB summary: gemcitabine pathway., Pharmacogenet Genomics
    Khatri A et al., 2014, SLC28A3 genotype and gemcitabine rate of infusion affect dFdCTP metabolite disposition in patients with solid tumours., Br J Cancer
  • ADENOSINE   SLC28A3

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23388705


    Sources:
    DTC

  • URIDINE   SLC28A3

    Interaction Score: 2.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23388705


    Sources:
    DTC

  • ZIDOVUDINE   SLC28A3

    Interaction Score: 0.66

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22960662


    Sources:
    PharmGKB

  • GEMCITABINE   SLC28A3

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25162786 24300978


    Sources:
    PharmGKB

  • DAUNORUBICIN   SLC28A3

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • DOXORUBICIN   SLC28A3

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Ensembl: ENSG00000197506

    • Version: 101_38

    Alternate Names:
    SLC28A3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: SLC28A3

    • Version: 18-August-2020

    Alternate Names:
    PA426 PharmGKB ID

    Gene Info:

    Publications:
    Visscher H et al., 2013, Validation of variants in SLC28A3 and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children., Pediatr Blood Cancer
    Visscher H et al., 2012, Pharmacogenomic prediction of anthracycline-induced cardiotoxicity in children., J Clin Oncol
    Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

  • DTC: SLC28A3

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Lepist EI et al., 2013, Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1., Drug Metab Dispos

  • HingoraniCasas: ENSG00000197506

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000197506 Gene Symbol
    SLC28A3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: SLC28A3

    • Version: 01-February-2022

    Alternate Names:
    CNT3 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

  • Pharos: SLC28A3

    • Version: 01-February-2022

    Alternate Names:
    Solute carrier family 28 member 3 Gene Name
    Q9HAS3 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSPORTER

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21