• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

SOX10 Gene Record

  • Summary
  • Interactions
  • Claims
  • SOX10 6663 Clinically ActionableDrug Resistance

    Alternate Names:

    6663
    SRY-BOX 10
    SOX10
    DOM
    PCWH
    WS2E
    WS4
    WS4C
    602229
    11190
    ENSG00000100146
    OTTHUMG00000149913
    5418
    PA36027
    SRY-BOX TRANSCRIPTION FACTOR 10
    SOX-10
    Transcription factor SOX-10
    P56693

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    DRUG RESISTANCE
    CLINICALLY ACTIONABLE
    TRANSCRIPTION FACTOR

    Publications:

    McWhinney-Glass S et al., 2013, Cumulative genetic risk predicts platinum/taxane-induced neurotoxicity., Clin Cancer Res
    Sun et al., 2014, Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma., Nature
  • VEMURAFENIB   SOX10

    Interaction Score: 1.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24670642


    Sources:
    CIViC

  • DOCETAXEL   SOX10

    Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23963862


    Sources:
    PharmGKB

  • CARBOPLATIN   SOX10

    Interaction Score: 0.39

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23963862


    Sources:
    PharmGKB

  • PACLITAXEL   SOX10

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23963862


    Sources:
    PharmGKB

  • Ensembl: ENSG00000100146

    • Version: 101_38

    Alternate Names:
    SOX10 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: SOX10

    • Version: 18-August-2020

    Alternate Names:
    PA36027 PharmGKB ID

    Gene Info:

    Publications:
    McWhinney-Glass S et al., 2013, Cumulative genetic risk predicts platinum/taxane-induced neurotoxicity., Clin Cancer Res

  • CIViC: SOX10

    • Version: 14-September-2020

    Alternate Names:
    6663 Entrez Gene ID
    5418 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Sun et al., 2014, Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma., Nature

  • Tempus: SOX10

    • Version: 11-November-2018

    Alternate Names:
    SOX10 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • Pharos: SOX10

    • Version: 01-February-2022

    Alternate Names:
    Transcription factor SOX-10 Gene Name
    P56693 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

  • FoundationOneGenes: SOX10

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: SOX10

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21