DGIdb - SREBF1 Gene Record

SREBF1 6720 Drug Resistance

Alternate Names:

6720
STEROL REGULATORY ELEMENT BINDING TRANSCRIPTION FACTOR 1
SREBF1
SREBP-1c
SREBP1
SREBP1a
bHLHd1
184756
11289
ENSG00000072310
OTTHUMG00000059313
P36956
PA335
HMD
IFAP2
Sterol regulatory element-binding protein 1

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

DRUG RESISTANCE
NUCLEAR HORMONE RECEPTOR
TRANSCRIPTION FACTOR

Publications:

Wagner et al., 2004, Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis., J. Lipid Res.
Zhang et al., 2003, SREBP-1 integrates the actions of thyroid hormone, insulin, cAMP, and medium-chain fatty acids on ACCalpha transcription in hepatocytes., J. Lipid Res.
Kotzka et al., 2000, Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade., J. Lipid Res.

INSULIN SREBF1

Interaction Score: 2.5

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14594997 12576518 10627507

Sources:
NCI
FLUVASTATIN SREBF1

Interaction Score: 1.52

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

Ensembl: ENSG00000072310
- Version: 101_38
Alternate Names:

SREBF1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
PharmGKB: SREBF1
- Version: 18-August-2020
Alternate Names:

PA335 PharmGKB ID

Gene Info:

Publications:

Vassas TJ et al., 2014, Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics., Pharmacogenomics

NCI: SREBF1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Kotzka et al., 2000, Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade., J. Lipid Res.

Zhang et al., 2003, SREBP-1 integrates the actions of thyroid hormone, insulin, cAMP, and medium-chain fatty acids on ACCalpha transcription in hepatocytes., J. Lipid Res.

Wagner et al., 2004, Defective uptake of triglyceride-associated fatty acids in adipose tissue causes the SREBP-1c-mediated induction of lipogenesis., J. Lipid Res.

GO: SREBF1
- Version: 01-May-2021
Alternate Names:

BHLHD1 GO Gene Synonym

SREBP1 GO Gene Synonym

Gene Info:

Gene Categories:

DRUG RESISTANCE, NUCLEAR HORMONE RECEPTOR

Publications:
Pharos: SREBF1
- Version: 01-May-2021
Alternate Names:

Sterol regulatory element-binding protein 1 Gene Name

P36956 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications: