DGIdb - STAT5A Gene Record

STAT5A 6776 Druggable GenomeClinically Actionable

Alternate Names:

6776
SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5A
STAT5A
MGF
STAT5
601511
11366
ENSG00000126561
OTTHUMG00000150725
P42229

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

KINASE
DRUGGABLE GENOME
CLINICALLY ACTIONABLE
TRANSCRIPTION FACTOR

Publications:

Jiang JK et al., 2008, Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550)., J Med Chem
Changelian PS et al., 2003, Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor., Science
Ioannidis et al., 2011, Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway., J. Med. Chem.

TOFACITINIB STAT5A

Interaction Score: 13.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19053756 14593182

Sources:
DTC
AZD-1480 STAT5A

Interaction Score: 12.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21138246

Sources:
DTC

Ensembl: ENSG00000126561
- Version: 101_38
Alternate Names:

STAT5A Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DTC: STAT5A

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Changelian PS et al., 2003, Prevention of organ allograft rejection by a specific Janus kinase 3 inhibitor., Science

Jiang JK et al., 2008, Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550)., J Med Chem

Ioannidis et al., 2011, Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway., J. Med. Chem.

HingoraniCasas: ENSG00000126561
- Version: 31-May-2017
Alternate Names:

ENSG00000126561 Gene Symbol

STAT5A Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Tempus: STAT5A
- Version: 11-November-2018
Alternate Names:

STAT5A Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
Pharos: STAT5A
- Version: 01-February-2022
Alternate Names:

Signal transducer and activator of transcription 5A Gene Name

P42229 UniProt ID

Gene Info:

Gene Categories:

KINASE, TRANSCRIPTION FACTOR

Publications:
FoundationOneGenes: STAT5A
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

Signal transducer and activator of transcription 5A	Gene Name
P42229	UniProt ID

STAT5A Gene Record

STAT5A 6776 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

TOFACITINIB STAT5A

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19053756 14593182

Sources: DTC

AZD-1480 STAT5A

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21138246

Sources: DTC

Ensembl: ENSG00000126561

Alternate Names: STAT5A Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DTC: STAT5A

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000126561

Alternate Names: ENSG00000126561 Gene Symbol STAT5A Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Tempus: STAT5A

Alternate Names: STAT5A Gene Symbol

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

Pharos: STAT5A

Alternate Names: Signal transducer and activator of transcription 5A Gene Name P42229 UniProt ID

Gene Info:

Gene Categories: KINASE, TRANSCRIPTION FACTOR

Publications:

FoundationOneGenes: STAT5A

Alternate Names:

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
19053756 14593182

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
21138246

Sources:
DTC

Alternate Names:

STAT5A Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000126561 Gene Symbol

STAT5A Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

STAT5A Gene Symbol

Gene Categories:

CLINICALLY ACTIONABLE

Alternate Names:

Signal transducer and activator of transcription 5A Gene Name

P42229 UniProt ID

Gene Categories:

KINASE, TRANSCRIPTION FACTOR

Gene Categories:

CLINICALLY ACTIONABLE