DGIdb - TAT Gene Record

TAT 6898

Alternate Names:

6898
TYROSINE AMINOTRANSFERASE
TAT
613018
11573
ENSG00000198650
OTTHUMG00000137590
BE0000692
P17735
2527
NM_000353
NP_000344

Gene Info:

Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	Catecholamine turnover
GuideToPharmacology Gene Category ID	766

(1 More Sources)

Gene Categories: Category Details

ENZYME

Publications:

Hannah et al., 1975, Stabilization of rat liver tyrosine aminotransferase by tetracycline., Biochem. J.
Vicent et al., 1998, Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives., J. Steroid Biochem. Mol. Biol.
Ozturk et al., 2006, Two novel mutations in the MEN1 gene in subjects with multiple endocrine neoplasia-1., J. Endocrinol. Invest.
Venetianer et al., 1981, Glucocorticoid responsiveness of hepatoma cell hybrids., Acta Biol Acad Sci Hung
Izawa et al., 1982, Dynamics of glucocorticoid receptor and induction of tyrosine aminotransferase in rat liver., Endocrinol. Jpn.
Schuetz et al., 1990, Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane., J. Biol. Chem.
Dong et al., 2007, 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells., Blood
Kohli et al., 1990, Expression and amplification of cloned rat liver tyrosine aminotransferase in nonhepatic cells., J. Cell. Physiol.
Tonner et al., 1997, Lead may affect glucocorticoid signal transduction in cultured hepatoma cells through inhibition of protein kinase C., Toxicology
Iwamoto et al., 1981, Insulin action in cultured HTC and H35 rat hepatoma cells: receptor binding and hormone sensitivity., Endocrinology
Luong et al., 1997, A continuous coupled spectrophotometric assay for tyrosine aminotransferase activity with aromatic and other nonpolar amino acids., Anal. Biochem.
De-Eknamkul et al., 1989, Behavior of Free Aromatic Amino Acid Pools in Rosmarinic Acid-Producing Cell Cultures of Anchusa officinalis L., Plant Physiol.
Patrizio et al., 2001, Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures., J. Neurochem.
Rege, 1987, Purification and characterization of a tyrosine aminotransferase from Crithidia fasciculata., Mol. Biochem. Parasitol.
Rego et al., 2008, Trypanosoma cruzi: characterisation of the gene encoding tyrosine aminotransferase in benznidazole-resistant and susceptible populations., Exp. Parasitol.
Shaffer et al., 2002, Quantitative chimeric analysis of six specificity determinants that differentiate Escherichia coli aspartate from tyrosine aminotransferase., Protein Sci.
Venhorst et al., 2003, Modeling and molecular dynamics of glutamine transaminase K/cysteine conjugate beta-lyase., J. Mol. Graph. Model.
Kim et al., 2006, Tat-mediated protein transduction of human brain pyridoxine-5-P oxidase into PC12 cells., J. Biochem. Mol. Biol.
Biagini et al., 2006, Hyperhomocysteinemia and hypercoagulability in primary biliary cirrhosis., World J. Gastroenterol.
Clayton et al., 2007, Hepatotoxin-induced hypertyrosinemia and its toxicological significance., Arch. Toxicol.

BENZNIDAZOLE TAT

Interaction Score: 4.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17678649

Sources:
NCI
PHENYLALANINE TAT

Interaction Score: 2.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9356140 16666560 11299302 2890101

Sources:
DrugBank
TYROSINE TAT

Interaction Score: 2.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17389761

Sources:
DrugBank
URIDINE TAT

Interaction Score: 0.97

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6161802

Sources:
NCI
ALBUMIN HUMAN TAT

Interaction Score: 0.58

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6127852

Sources:
NCI
TETRACYCLINE TAT

Interaction Score: 0.51

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
2154

Sources:
NCI
PYRIDOXAL PHOSPHATE TAT

Interaction Score: 0.5

Interaction Types & Directionality:

cofactor (activating)

Interaction Info:

PMIDs:
12441383 12798391 16466641 16570355 16902803

Sources:
DrugBank
PREDNISOLONE TAT

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
6127207

Sources:
NCI
PHENOBARBITAL TAT

Interaction Score: 0.23

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1688552

Sources:
NCI
GENISTEIN TAT

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9128187

Sources:
NCI
GLUTAMIC ACID TAT

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16840830

Sources:
DrugBank
PROGESTERONE TAT

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9744518

Sources:
NCI
METHOTREXATE TAT

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
1967611

Sources:
NCI

Ensembl: ENSG00000198650
- Version: 101_38
Alternate Names:

TAT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
GuideToPharmacology: 6898
- Version: 29-September-2020
Alternate Names:

11573 HUGO Gene ID

11573 HUGO Gene Symbol

tyrosine aminotransferase HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Catecholamine turnover

GuideToPharmacology Gene Category ID 766

Gene Categories:

ENZYME

Publications:

DrugBank: BE0000692

Version: 5.1.7

Alternate Names:

TAT DrugBank Gene Name

P17735 UniProt Accession

6898 Entrez Gene Id

Gene Info:

Publications:

Dong et al., 2007, 14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells., Blood

Patrizio et al., 2001, Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures., J. Neurochem.

De-Eknamkul et al., 1989, Behavior of Free Aromatic Amino Acid Pools in Rosmarinic Acid-Producing Cell Cultures of Anchusa officinalis L., Plant Physiol.

NCI: TAT

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Vicent et al., 1998, Influence of calf serum on glucocorticoid-responses of certain progesterone derivatives., J. Steroid Biochem. Mol. Biol.

Tonner et al., 1997, Lead may affect glucocorticoid signal transduction in cultured hepatoma cells through inhibition of protein kinase C., Toxicology

Bracken et al., 1987, Induction of metallothionein by steroids in rat primary hepatocyte cultures., Toxicol. Appl. Pharmacol.

HumanProteinAtlas: TAT
- Version: 19.3
Alternate Names:

ENSG00000198650 Ensembl Gene ID

Tyrosine aminotransferase Human Protein Atlas Gene Description

P17735 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

11573	HUGO Gene ID
11573	HUGO Gene Symbol
tyrosine aminotransferase	HUGO Gene Name

TAT	DrugBank Gene Name
P17735	UniProt Accession
6898	Entrez Gene Id

ENSG00000198650	Ensembl Gene ID
Tyrosine aminotransferase	Human Protein Atlas Gene Description
P17735	UniProt ID

TAT Gene Record

TAT 6898

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17678649

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9356140 16666560 11299302 2890101

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17389761

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6161802

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6127852

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 2154

Sources: NCI

Interaction Types & Directionality: cofactor (activating)

Interaction Info:

PMIDs: 12441383 12798391 16466641 16570355 16902803

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 6127207

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1688552

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9128187

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16840830

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9744518

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 1967611

Sources: NCI

Ensembl: ENSG00000198650

Alternate Names: TAT Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

GuideToPharmacology: 6898

Alternate Names: 11573 HUGO Gene ID 11573 HUGO Gene Symbol tyrosine aminotransferase HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name Catecholamine turnover GuideToPharmacology Gene Category ID 766

Gene Categories: ENZYME

Publications:

DrugBank: BE0000692

Alternate Names: TAT DrugBank Gene Name P17735 UniProt Accession 6898 Entrez Gene Id

Gene Info:

NCI: TAT

Alternate Names:

Gene Info:

HumanProteinAtlas: TAT

Alternate Names: ENSG00000198650 Ensembl Gene ID Tyrosine aminotransferase Human Protein Atlas Gene Description P17735 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
17678649

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9356140 16666560 11299302 2890101

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17389761

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
6161802

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
6127852

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
2154

Sources:
NCI

Interaction Types & Directionality:

cofactor (activating)

PMIDs:
12441383 12798391 16466641 16570355 16902803

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
6127207

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1688552

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9128187

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16840830

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
9744518

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
1967611

Sources:
NCI

Alternate Names:

TAT Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

11573 HUGO Gene ID

11573 HUGO Gene Symbol

tyrosine aminotransferase HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Catecholamine turnover

GuideToPharmacology Gene Category ID 766

Gene Categories:

ENZYME

Alternate Names:

TAT DrugBank Gene Name

P17735 UniProt Accession

6898 Entrez Gene Id

Alternate Names:

ENSG00000198650 Ensembl Gene ID

Tyrosine aminotransferase Human Protein Atlas Gene Description

P17735 UniProt ID

Gene Categories:

ENZYME