• TBXAS1 6916 Druggable Genome

    Alternate Names:

    6916
    THROMBOXANE A SYNTHASE 1
    TBXAS1
    BDPLT14
    CYP5
    CYP5A1
    GHOSAL
    THAS
    TS
    TXAS
    TXS
    274180
    11609
    ENSG00000059377
    OTTHUMG00000157302
    THROMBOXANE-A SYNTHASE (EC 5.3.99.5) (TXA SYNTHASE) (TXS). [SOURCE:UNIPROT/SWISSPROT;ACC:P24557]
    P24557
    THROMBOXANE-A SYNTHASE
    1353
    PA349
    THAS_HUMAN
    T78356

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Target Class Enzymes
    Target Subclass EC:5.3.99.5
    GuideToPharmacology Gene Category Name CYP5, CYP7 and CYP8 families
    GuideToPharmacology Gene Category ID 265
    Interpro Short Name Cyt_P450
    Interpro Acc IPR001128
    Interpro Type Family
    Human Readable Name CYTOCHROME P450
    Interpro Name Cytochrome P450
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Prostaglandin synthases
    GuideToPharmacology Gene Category ID 270
    (6 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    CYTOCHROME P450
    ENZYME
  • Interaction Score: 21.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Inhibition of thromboxane A2 synthetase activity in human washed platelets.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 21.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • Interaction Score: 0.58

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21449675


    Sources:
    PharmGKB