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TDO2 Gene Record

  • Summary
  • Interactions
  • Claims
  • TDO2 6999 Druggable Genome

    Alternate Names:

    6999
    TRYPTOPHAN 2,3-DIOXYGENASE
    TDO2
    TDO
    TO
    TPH2
    TRPO
    191070
    11708
    ENSG00000151790
    OTTHUMG00000161838
    P48775
    T44818
    HYPTRP

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Grote et al., 1983, No correlation between binding of glucocorticosteroids to specific cytoplasmic proteins in vivo and enzyme induction in the rat liver., Biochem. J.
    Schubart, 1986, Regulation of gene expression in rat hepatocytes and hepatoma cells by insulin: quantitation of messenger ribonucleic acid's coding for tyrosine aminotransferase, tryptophan oxygenase, and phosphoenolpyruvate carboxykinase., Endocrinology
  • INSULIN   TDO2

    Interaction Score: 1.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2875868


    Sources:
    NCI

  • DEXAMETHASONE   TDO2

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6136271


    Sources:
    NCI

  • Ensembl: ENSG00000151790

    • Version: 101_38

    Alternate Names:
    TDO2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: TDO2

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Grote et al., 1983, No correlation between binding of glucocorticosteroids to specific cytoplasmic proteins in vivo and enzyme induction in the rat liver., Biochem. J.
    Li et al., 1995, Subchronic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and their reversibility in male Sprague-Dawley rats., Toxicology
    Schubart, 1986, Regulation of gene expression in rat hepatocytes and hepatoma cells by insulin: quantitation of messenger ribonucleic acid's coding for tyrosine aminotransferase, tryptophan oxygenase, and phosphoenolpyruvate carboxykinase., Endocrinology

  • HingoraniCasas: ENSG00000151790

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000151790 Gene Symbol
    TDO2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: TDO2

    • Version: 19.3

    Alternate Names:
    ENSG00000151790 Ensembl Gene ID
    TDO Human Protein Atlas Gene Synonym
    TPH2 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • TTD: Tryptophan 2,3-dioxygenase

    • Version: 2020.06.01

    Alternate Names:
    TDO TTD Gene Abbreviation
    T44818 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: TDO2

    • Version: 01-February-2022

    Alternate Names:
    Tryptophan 2,3-dioxygenase Gene Name
    P48775 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21