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TGFBR3 Gene Record

  • Summary
  • Interactions
  • Claims
  • TGFBR3 7049 Druggable Genome

    Alternate Names:

    7049
    TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3
    TGFBR3
    BGCAN
    betaglycan
    600742
    11774
    ENSG00000069702
    OTTHUMG00000010097
    Q03167
    PA36487

    Gene Info:

    Target Class Receptors
    Target Subclass Receptor
    Target Subclass TGFR
    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

    Nakayama et al., 1994, Dexamethasone enhancement of betaglycan (TGF-beta type III receptor) gene expression in osteoblast-like cells., Exp. Cell Res.
    Chen et al., 2003, GM-CSF increases airway smooth muscle cell connective tissue expression by inducing TGF-beta receptors., Am. J. Physiol. Lung Cell Mol. Physiol.
  • REGRAMOSTIM   TGFBR3

    Interaction Score: 4.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12471017


    Sources:
    NCI

  • DEXAMETHASONE   TGFBR3

    Interaction Score: 0.74

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8143777


    Sources:
    NCI

  • Ensembl: ENSG00000069702

    • Version: 101_38

    Alternate Names:
    TGFBR3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: Q03167

    • Version: January-2014

    Alternate Names:
    TGFBR3 Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptor
    Target Subclass TGFR

    Publications:

  • PharmGKB: TGFBR3

    • Version: 18-August-2020

    Alternate Names:
    PA36487 PharmGKB ID

    Gene Info:

    Publications:
    Ganea K et al., 2012, Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response., Transl Psychiatry

  • NCI: TGFBR3

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Andres et al., 1992, Binding of two growth factor families to separate domains of the proteoglycan betaglycan., J. Biol. Chem.
    Hernández-Pando et al., 2006, A combination of a transforming growth factor-beta antagonist and an inhibitor of cyclooxygenase is an effective treatment for murine pulmonary tuberculosis., Clin. Exp. Immunol.
    Slimani et al., 2003, Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages., Biochim. Biophys. Acta

  • HingoraniCasas: ENSG00000069702

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000069702 Gene Symbol
    TGFBR3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: TGFBR3

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21