• TMPRSS2 7113 Druggable GenomeClinically Actionable

    Alternate Names:

    7113
    TRANSMEMBRANE PROTEASE, SERINE 2
    TMPRSS2
    PP9284
    PRSS10
    602060
    11876
    ENSG00000184012
    OTTHUMG00000086762
    TRANSMEMBRANE PROTEASE, SERINE 2 PRECURSOR (EC 3.4.21.-). [SOURCE:UNIPROT/SWISSPROT;ACC:O15393]
    TMPS2_HUMAN
    O15393
    TRANSMEMBRANE PROTEASE SERINE 2 NON-CATALYTIC CHAIN
    2421
    NP_001128571|NP_005647
    NM_001135099|NM_005656
    transmembrane serine protease 2

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name PROTEASE
    Interpro Name Peptidase S1/S6, chymotrypsin/Hap
    Interpro Short Name Peptidase_S1_S6
    Uniprot Status Swiss-Prot
    Interpro Acc IPR001190
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR001254
    Interpro Type Domain
    Interpro Name Speract/scavenger receptor
    Interpro Short Name Srcr_rcpt
    GuideToPharmacology Gene Category Name S1: Chymotrypsin
    GuideToPharmacology Gene Category ID 751
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME
  • Interaction Score: 21.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Inhibition of TMPRSS2-dependent MERS-S-mediated membrane fusion in an in vitro reporter assay.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    32142651


  • Interaction Score: 2.9

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    TMPRSS2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    TRANSMEMBRANE PROTEASE, SERINE 2 PRECURSOR (EC 3.4.21.-). [SOURCE:UNIPROT/SWISSPROT;ACC:O15393] Description
    TMPRSS2 Display Id
    ENSG00000184012 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    TMPRSS2 Uniprot Gene Name
    TRANSMEMBRANE PROTEASE SERINE 2 NON-CATALYTIC CHAIN Uniprot Protein Name
    TMPS2_HUMAN Uniprot Id

    Gene Info:
    Interpro Name Peptidase S1/S6, chymotrypsin/Hap
    Human Readable Name PROTEASE
    Interpro Short Name Peptidase_S1_S6

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    11876 HUGO Gene ID
    11876 HUGO Gene Symbol
    transmembrane serine protease 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name S1: Chymotrypsin
    GuideToPharmacology Gene Category ID 751

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000184012 Gene Symbol
    TMPRSS2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-November-2018

    Alternate Names:
    TMPRSS2 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    7113 Gene ID
    PP9284 dGene Synonym
    PRSS10 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: