• TNFRSF9 3604 Druggable Genome

    Alternate Names:

    3604
    TNF RECEPTOR SUPERFAMILY MEMBER 9
    TNFRSF9
    4-1BB
    CD137
    CDw137
    ILA
    602250
    11924
    ENSG00000049249
    OTTHUMG00000001223
    1878
    Q07011
    CD_antigen=CD137
    T-cell antigen ILA
    T-cell antigen 4-1BB homolog
    4-1BB ligand receptor
    Tumor necrosis factor receptor superfamily member 9
    Co-stimulatory molecule 4-1BB
    T93923
    NM_003811
    NP_003802
    BE0003463

    Gene Info:

    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Tumour necrosis factor (TNF) receptor family
    GuideToPharmacology Gene Category ID 334
    (4 More Sources)

    Gene Categories: Category Details

    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 113.61

    Interaction Types & Directionality:
    agonist (activating)
    antibody (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Dissociation constant for the 20H4-9-IgG4 clone binding to human 4-1BB
    Specific Action of the Ligand Agonist
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 56.81

    Interaction Types & Directionality:
    antibody (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Endogenous Drug? False
    Specific Action of the Ligand Agonist

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    TNFRSF9 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    11924 HUGO Gene ID
    11924 HUGO Gene Symbol
    TNF receptor superfamily member 9 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Tumour necrosis factor (TNF) receptor family
    GuideToPharmacology Gene Category ID 334

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000049249 Gene Symbol
    TNFRSF9 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    ILA GENE_SYMBOL
    TNFRSF9 GENE_SYMBOL
    Tumor necrosis factor receptor superfamily member 9 UNIPROT

    Gene Info:

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    CD137 GO Gene Synonym
    ILA GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

    • Version: 11-November-2018

    Alternate Names:
    TNFRSF9 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

    • Version: 5.1.7

    Alternate Names:
    TNFRSF9 DrugBank Gene Name
    Q07011 UniProt Accession
    3604 Entrez Gene Id

    Gene Info:

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    CD137 TTD Gene Abbreviation
    T93923 TTD Target ID

    Gene Info:

    Publications: