• TRPV3 162514 Druggable Genome

    Alternate Names:

    162514
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3
    TRPV3
    FNEPPK2
    OLMS
    VRL3
    607066
    18084
    ENSG00000167723
    OTTHUMG00000090695
    VRL-3
    Vanilloid receptor-like 3
    Q8NET8
    TRPV3_HUMAN
    509
    NP_659505
    NM_145068
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3 (TRPV3) (VANILLOID RECEPTOR-LIKE 3) (VRL-3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8NET8]
    Transient receptor potential cation channel V3
    T58496
    OLMS1

    Gene Info:

    Target Subclass Channels
    Target Subclass TRP_channels
    Transmembrane Helix Count 6
    Target Subclass Voltage_gated_ion_channels
    Target Main Class Transporters
    GuideToPharmacology Gene Category Name Transient Receptor Potential channels
    GuideToPharmacology Gene Category ID 78
    Uniprot Status Swiss-Prot
    Interpro Acc IPR005821
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Interpro Name Ion transport domain
    Interpro Short Name Ion_trans_dom
    Target Class Transporters
    Target Subclass TC:1.A.4.2.9
    Initial Gene Query TRPV3
    Counted Citations from 1950-2000 116
    Gene Biotype PROTEIN_CODING
    (9 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 15.95

    Interaction Types & Directionality:
    inducer (activating)

    Interaction Info:
    Trial Name -
    Novel drug target Established target

    PMIDs:
    16829128


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16998480


    Sources:
    DTC

  • Interaction Score: 7.97

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Transient receptor potential cation channel subfamily V member 3 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    TRPV3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3 (TRPV3) (VANILLOID RECEPTOR-LIKE 3) (VRL-3). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8NET8] Description
    TRPV3 Display Id
    ENSG00000167723 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-August-2011

    Alternate Names:
    TRPV3_HUMAN Uniprot Id
    TRPV3 Gene Symbol
    Q8NET8 Uniprot Accession

    Gene Info:
    Target Subclass Channels
    Target Subclass TRP_channels
    Transmembrane Helix Count 6

    Publications:

    • Version: February-2014

    Alternate Names:
    162514 Entrez Gene ID

    Gene Info:
    Initial Gene Query TRPV3
    Counted Citations from 1950-2000 116

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: January-2014

    Alternate Names:
    TRPV3 Gene Symbol

    Gene Info:
    Target Class Transporters
    Target Subclass TC:1.A.4.2.9

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    TRPV3 Uniprot Gene Name
    Q8NET8 Uniprot Accession
    ENSG00000167723 Ensembl Gene Id

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR005821
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    18084 HUGO Gene ID
    18084 HUGO Gene Symbol
    transient receptor potential cation channel subfamily V member 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Transient Receptor Potential channels
    GuideToPharmacology Gene Category ID 78

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000167723 Gene Symbol
    TRPV3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    TRPV3 GENE_SYMBOL
    Transient receptor potential cation channel subfamily V member 3 UNIPROT
    Vanilloid receptor-like 3 UNIPROT

    Gene Info:

    Publications:

  • Alternate Names:
    TRPV3 TTD Gene Abbreviation
    T58496 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Transient receptor potential cation channel subfamily V member 3 Gene Name
    Q8NET8 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 01-May-2021

    Alternate Names:

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: