• TRPV4 59341 Druggable Genome

    Alternate Names:

    59341
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4
    TRPV4
    BCYM3
    CMT2C
    HMSN2C
    OTRPC4
    SMAL
    SPSMA
    SSQTL1
    TRP12
    VRL2
    VROAC
    605427
    18083
    ENSG00000111199
    OTTHUMG00000169277
    VRL-2
    Transient receptor potential protein 12
    Osm-9-like TRP channel 4
    VR-OAC
    Vanilloid receptor-related osmotically-activated channel
    Vanilloid receptor-like protein 2
    Vanilloid receptor-like channel 2
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 (TRPV4) (OSM-9-LIKE TRP CHANNEL 4) (OTRPC4) (VANILLOID RECEPTOR-LIKE CHANNEL 2) (VANILLOID RECEPTOR-LIKE PROTEIN 2) (VRL-2) (VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL) (VR-OAC
    Q9HBA0
    TRPV4_HUMAN
    510
    NP_067638
    NM_021625
    Transient receptor potential cation channel V4
    T64213

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR005821
    Interpro Name Ion transport domain
    Interpro Type Domain
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Uniprot Status Swiss-Prot
    GuideToPharmacology Gene Category Name Transient Receptor Potential channels
    GuideToPharmacology Gene Category ID 78
    Initial Gene Query TRPV4
    Counted Citations from 1950-2000 388
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME
  • Interaction Score: 63.79

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Transient receptor potential cation channel subfamily V member 4 antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 21.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16998480


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    TRPV4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    59341 Entrez Gene ID

    Gene Info:
    Initial Gene Query TRPV4
    Counted Citations from 1950-2000 388

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 (TRPV4) (OSM-9-LIKE TRP CHANNEL 4) (OTRPC4) (VANILLOID RECEPTOR-LIKE CHANNEL 2) (VANILLOID RECEPTOR-LIKE PROTEIN 2) (VRL-2) (VANILLOID RECEPTOR-RELATED OSMOTICALLY ACTIVATED CHANNEL) (VR-OAC Description
    ENSG00000111199 Ensembl Gene Id
    TRPV4 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    TRPV4_HUMAN Uniprot Id
    59341 Entrez Gene Id
    TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4 Uniprot Protein Name

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Interpro Acc IPR005821
    Interpro Name Ion transport domain

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    18083 HUGO Gene ID
    18083 HUGO Gene Symbol
    transient receptor potential cation channel subfamily V member 4 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Transient Receptor Potential channels
    GuideToPharmacology Gene Category ID 78

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 02-September-2020
    • Version: chembl_23

    Alternate Names:
    VROAC GENE_SYMBOL
    TRPV4 GENE_SYMBOL
    VRL2 GENE_SYMBOL

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000111199 Gene Symbol
    TRPV4 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000111199 Ensembl Gene ID
    CMT2C Human Protein Atlas Gene Synonym
    OTRPC4 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

  • Alternate Names:
    TRPV4 TTD Gene Abbreviation
    T64213 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    VRL2 GO Gene Synonym
    VROAC GO Gene Synonym

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Transient receptor potential cation channel subfamily V member 4 Gene Name
    Q9HBA0 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: