• TTK 7272 Druggable Genome

    Alternate Names:

    7272
    TTK PROTEIN KINASE
    TTK
    CT96
    ESK
    MPH1
    MPS1
    MPS1L1
    PYT
    604092
    12401
    ENSG00000112742
    OTTHUMG00000015088
    P33981
    DUAL SPECIFICITY PROTEIN KINASE TTK
    TTK_HUMAN
    DUAL SPECIFICITY PROTEIN KINASE TTK (EC 2.7.1.-) (PHOSPHOTYROSINE PICKED THREONINE KINASE) (PYT). [SOURCE:UNIPROT/SWISSPROT;ACC:P33981]
    2264
    NP_003309
    NM_001166691
    Phosphotyrosine picked threonine-protein kinase
    T74977

    Gene Info:

    Uniprot Status Swiss-Prot
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Uniprot Evidence 1: Evidence at protein level
    GuideToPharmacology Gene Category Name TTK family
    GuideToPharmacology Gene Category ID 637
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 42.53

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? True
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


  • Interaction Score: 21.26

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Dual specificity protein kinase TTK inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.53

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    TTK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    P33981 Uniprot Accession
    TTK Uniprot Gene Name
    ENSG00000112742 Ensembl Gene Id

    Gene Info:
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    DUAL SPECIFICITY PROTEIN KINASE TTK (EC 2.7.1.-) (PHOSPHOTYROSINE PICKED THREONINE KINASE) (PYT). [SOURCE:UNIPROT/SWISSPROT;ACC:P33981] Description
    TTK Display Id
    ENSG00000112742 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    12401 HUGO Gene ID
    12401 HUGO Gene Symbol
    TTK protein kinase HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name TTK family
    GuideToPharmacology Gene Category ID 637

    Gene Categories:
    ENZYME

    Publications:

  • DTC: TTK

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000112742 Gene Symbol
    TTK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    MPS1L1 GENE_SYMBOL
    TTK GENE_SYMBOL
    Dual specificity protein kinase TTK UNIPROT

    Gene Info:

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    7272 Gene ID
    CT96 dGene Synonym
    ESK dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Alternate Names:
    MPS1 TTD Gene Abbreviation
    T74977 TTD Target ID

    Gene Info:

    Publications:

  • GO: TTK

    • Version: 01-May-2021

    Alternate Names:
    MPS1 GO Gene Synonym
    MPS1L1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, TYROSINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Dual specificity protein kinase TTK Gene Name
    P33981 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: