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TYMSOS Gene Record

  • Summary
  • Interactions
  • Claims
  • TYMSOS 494514

    Alternate Names:

    494514
    TYMS OPPOSITE STRAND
    TYMSOS
    C18orf56
    29553
    PA134956204
    ENSG00000176912
    TYMS OPPOSITE STRAND RNA

    Gene Info:

    Gene Biotype LNCRNA
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Lee MN et al., 2015, Impact of Genetic Polymorphisms on 6-Thioguanine Nucleotide Levels and Toxicity in Pediatric Patients with IBD Treated with Azathioprine., Inflamm Bowel Dis
    Joerger M et al., 2015, Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy., Cancer Chemother Pharmacol
    James HM et al., 2008, Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis., J Rheumatol
  • HYDROXYCHLOROQUINE   TYMSOS

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18322994


    Sources:
    PharmGKB

  • PLATINUM   TYMSOS

    Interaction Score: 0.68

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25677447


    Sources:
    PharmGKB

  • SULFASALAZINE   TYMSOS

    Interaction Score: 0.41

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18322994


    Sources:
    PharmGKB

  • AZATHIOPRINE   TYMSOS

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    26332308


    Sources:
    PharmGKB

  • ASPARAGINASE   TYMSOS

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CAPECITABINE   TYMSOS

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25677447


    Sources:
    PharmGKB

  • PREDNISONE   TYMSOS

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • MERCAPTOPURINE   TYMSOS

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CYTARABINE   TYMSOS

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • ETOPOSIDE   TYMSOS

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • IRINOTECAN   TYMSOS

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • DAUNORUBICIN   TYMSOS

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • DEXAMETHASONE   TYMSOS

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • Ensembl: ENSG00000176912

    • Version: 101_38

    Alternate Names:
    TYMSOS Ensembl Gene Name

    Gene Info:
    Gene Biotype LNCRNA

    Publications:

  • PharmGKB: C18orf56

    • Version: 18-August-2020

    Alternate Names:
    PA134956204 PharmGKB ID

    Gene Info:

    Publications:
    Lee MN et al., 2015, Impact of Genetic Polymorphisms on 6-Thioguanine Nucleotide Levels and Toxicity in Pediatric Patients with IBD Treated with Azathioprine., Inflamm Bowel Dis
    Joerger M et al., 2015, Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy., Cancer Chemother Pharmacol
    James HM et al., 2008, Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis., J Rheumatol

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21