DGIdb - UCP1 Gene Record

UCP1 7350 Druggable Genome

Alternate Names:

7350
UNCOUPLING PROTEIN 1
UCP1
SLC25A7
UCP
113730
12517
ENSG00000109424
OTTHUMG00000133415
P25874
MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 (UCP 1) (THERMOGENIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P25874]
1066
Mitochondrial uncoupling protein 1
T88729
Mitochondrial brown fat uncoupling protein 1

Gene Info:

Human Readable Name	DRUGGABLE GENOME
GuideToPharmacology Gene Category Name	Mitochondrial uncoupling proteins
GuideToPharmacology Gene Category ID	207
Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

TRANSPORTER
ION CHANNEL
DRUGGABLE GENOME

Publications:

Burcelin et al., 1993, Changes in uncoupling protein and GLUT4 glucose transporter expressions in interscapular brown adipose tissue of diabetic rats: relative roles of hyperglycaemia and hypoinsulinaemia., Biochem. J.
Sivitz et al., 1999, Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats., Am. J. Physiol.
Urhammer et al., 1997, Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity., J. Clin. Endocrinol. Metab.
Urhammer et al., 2000, Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects., J. Clin. Endocrinol. Metab.

METYROSINE UCP1

Interaction Score: 3.87

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10516126

Sources:
NCI
INSULIN UCP1

Interaction Score: 1.25

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9398715 10999801

Sources:
NCI
STREPTOZOCIN UCP1

Interaction Score: 0.92

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
8471028

Sources:
NCI

Ensembl: ENSG00000109424
- Version: 101_38
Alternate Names:

UCP1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
RussLampel: ENSG00000109424
- Version: 26-July-2011
Alternate Names:

ENSG00000109424 Ensembl Gene Id

UCP1 Display Id

MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 (UCP 1) (THERMOGENIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P25874] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
GuideToPharmacology: 7350
- Version: 29-September-2020
Alternate Names:

12517 HUGO Gene ID

12517 HUGO Gene Symbol

uncoupling protein 1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Mitochondrial uncoupling proteins

GuideToPharmacology Gene Category ID 207

Gene Categories:

TRANSPORTER

Publications:

NCI: UCP1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Sivitz et al., 1999, Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats., Am. J. Physiol.

Urhammer et al., 1997, Studies of genetic variability of the uncoupling protein 1 gene in Caucasian subjects with juvenile-onset obesity., J. Clin. Endocrinol. Metab.

Urhammer et al., 2000, Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects., J. Clin. Endocrinol. Metab.

TTD: Mitochondrial uncoupling protein 1
- Version: 2020.06.01
Alternate Names:

UCP1 TTD Gene Abbreviation

T88729 TTD Target ID

Gene Info:

Publications:
Pharos: UCP1
- Version: 01-May-2021
Alternate Names:

Mitochondrial brown fat uncoupling protein 1 Gene Name

P25874 UniProt ID

Gene Info:

Gene Categories:

TRANSPORTER, ION CHANNEL

Publications:

ENSG00000109424	Ensembl Gene Id
UCP1	Display Id
MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 (UCP 1) (THERMOGENIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P25874]	Description

12517	HUGO Gene ID
12517	HUGO Gene Symbol
uncoupling protein 1	HUGO Gene Name

Mitochondrial brown fat uncoupling protein 1	Gene Name
P25874	UniProt ID

UCP1	TTD Gene Abbreviation
T88729	TTD Target ID

UCP1 Gene Record

UCP1 7350 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

METYROSINE UCP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10516126

Sources: NCI

INSULIN UCP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9398715 10999801

Sources: NCI

STREPTOZOCIN UCP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 8471028

Sources: NCI

Ensembl: ENSG00000109424

Alternate Names: UCP1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000109424

Alternate Names: ENSG00000109424 Ensembl Gene Id UCP1 Display Id MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 (UCP 1) (THERMOGENIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P25874] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

GuideToPharmacology: 7350

Alternate Names: 12517 HUGO Gene ID 12517 HUGO Gene Symbol uncoupling protein 1 HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name Mitochondrial uncoupling proteins GuideToPharmacology Gene Category ID 207

Gene Categories: TRANSPORTER

Publications:

NCI: UCP1

Alternate Names:

Gene Info:

TTD: Mitochondrial uncoupling protein 1

Alternate Names: UCP1 TTD Gene Abbreviation T88729 TTD Target ID

Gene Info:

Publications:

Pharos: UCP1

Alternate Names: Mitochondrial brown fat uncoupling protein 1 Gene Name P25874 UniProt ID

Gene Info:

Gene Categories: TRANSPORTER, ION CHANNEL

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
10516126

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9398715 10999801

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
8471028

Sources:
NCI

Alternate Names:

UCP1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000109424 Ensembl Gene Id

UCP1 Display Id

MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1 (UCP 1) (THERMOGENIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P25874] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

12517 HUGO Gene ID

12517 HUGO Gene Symbol

uncoupling protein 1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Mitochondrial uncoupling proteins

GuideToPharmacology Gene Category ID 207

Gene Categories:

TRANSPORTER

Alternate Names:

UCP1 TTD Gene Abbreviation

T88729 TTD Target ID

Alternate Names:

Mitochondrial brown fat uncoupling protein 1 Gene Name

P25874 UniProt ID

Gene Categories:

TRANSPORTER, ION CHANNEL