• ZAP70 7535 Druggable Genome

    Alternate Names:

    7535
    ZETA CHAIN OF T-CELL RECEPTOR ASSOCIATED PROTEIN KINASE 70
    ZAP70
    ADMIO2
    IMD48
    SRK
    STCD
    STD
    TZK
    ZAP-70
    176947
    12858
    ENSG00000115085
    OTTHUMG00000153060
    P43403
    ZAP70_HUMAN
    TYROSINE-PROTEIN KINASE ZAP-70
    2285
    NP_001070
    NM_001079
    TYROSINE-PROTEIN KINASE ZAP-70 (EC 2.7.1.112) (70 KDA ZETA-ASSOCIATED PROTEIN) (SYK-RELATED TYROSINE KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P43403]
    zeta chain of T cell receptor associated protein kinase 70
    T64553

    Gene Info:

    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name KINASE
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Acc IPR001245
    Interpro Type Domain
    GuideToPharmacology Gene Category Name Syk family
    GuideToPharmacology Gene Category ID 625
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    ENZYME
  • Interaction Score: 21.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17897956


    Sources:
    DTC

  • Interaction Score: 10.63

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found