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ZEB1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ZEB1 6935 Drug Resistance

    Alternate Names:

    6935
    ZINC FINGER E-BOX BINDING HOMEOBOX 1
    ZEB1
    AREB6
    BZP
    DELTAEF1
    FECD6
    NIL2A
    PPCD3
    TCF8
    ZFHEP
    ZFHX1A
    189909
    11642
    ENSG00000148516
    OTTHUMG00000017907
    5649
    P37275
    Zinc finger E-box-binding homeobox 1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUG RESISTANCE
    TRANSCRIPTION FACTOR

    Publications:

    Sánchez-Tilló et al., 2014, The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma., Cell Death Differ.
    Guo C et al., 2017, ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells., J Cancer
  • SALINOMYCIN   ZEB1

    Interaction Score: 41.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24013721


    Sources:
    CIViC

  • OXALIPLATIN   ZEB1

    Interaction Score: 1.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29151941


    Sources:
    CIViC

  • DOXORUBICIN   ZEB1

    Interaction Score: 0.44

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24013721


    Sources:
    CIViC

  • Ensembl: ENSG00000148516

    • Version: 101_38

    Alternate Names:
    ZEB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • CIViC: ZEB1

    • Version: 14-September-2020

    Alternate Names:
    6935 Entrez Gene ID
    5649 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Sánchez-Tilló et al., 2014, The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma., Cell Death Differ.
    Guo C et al., 2017, ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells., J Cancer

  • Pharos: ZEB1

    • Version: 01-February-2022

    Alternate Names:
    Zinc finger E-box-binding homeobox 1 Gene Name
    P37275 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21