DGIdb - ANISTREPLASE Drug Record

ANISTREPLASE chembl:CHEMBL2108250 Approved

Alternate Names:

ANISTREPLASE
EMINASE
APSAC
BRL-26921
TISSUE-TYPE PLASMINOGEN ACTIVATOR PRECURSOR
T-PLASMINOGEN ACTIVATOR
T- PA
TPA
chemidplus:81669-57-0
drugbank:00029
chembl:CHEMBL2108250
rxcui:40028

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	protein
Drug Indications	Thrombolytic Agents
Year of Approval	not approved by the fda
Drug Class	thrombolytic agents

(0 More Sources)

Publications:

Melandri et al., 2009, Review of tenecteplase (TNKase) in the treatment of acute myocardial infarction., Vasc Health Risk Manag
Longstaff et al., 2008, Fibrin binding and the regulation of plasminogen activators during thrombolytic therapy., Cardiovasc Hematol Agents Med Chem
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Hilleman et al., 2007, Fibrinolytic agents for the management of ST-segment elevation myocardial infarction., Pharmacotherapy
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Prowse CV et al., 1982, Proteolysis of fibrinogen in healthy volunteers following major and minor vivo plasminogen activation., Thromb Res
Merlini PA et al., 1995, Thrombin generation and activity during thrombolysis and concomitant heparin therapy in patients with acute myocardial infarction., J Am Coll Cardiol

ANISTREPLASE FGA

Interaction Score: 19.32

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
17016423 17139284 6750837 7798503

Sources:
TdgClinicalTrial
ANISTREPLASE PLG

Interaction Score: 7.46

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
19436656 18673235 11752352 17963464

Sources:
TdgClinicalTrial TEND TTD

TEND: ANISTREPLASE
- Version: 01-August-2011
Alternate Names:

ANISTREPLASE Primary Drug Name

Drug Info:

Drug Class thrombolytic agents

Year of Approval not approved by the fda

Publications:
TdgClinicalTrial: ANISTREPLASE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Thrombolytic Agents

Drug Class protein

FDA Approval not approved by the FDA

Publications:
TTD: Anistreplase
- Version: 2020.06.01
Alternate Names:

D0K4DI TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL2108250
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	-

Novel drug target	Established target
Trial Name	-

ANISTREPLASE Drug Record

ANISTREPLASE chembl:CHEMBL2108250 Approved

Alternate Names:

Drug Info:

Publications:

ANISTREPLASE FGA

Interaction Types & Directionality: n/a

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 17016423 17139284 6750837 7798503

Sources: TdgClinicalTrial

ANISTREPLASE PLG

Interaction Types & Directionality: activator (activating)

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 19436656 18673235 11752352 17963464

Sources: TdgClinicalTrial TEND TTD

TEND: ANISTREPLASE

Alternate Names: ANISTREPLASE Primary Drug Name

Drug Info: Drug Class thrombolytic agents Year of Approval not approved by the fda

Publications:

TdgClinicalTrial: ANISTREPLASE

Alternate Names:

Drug Info: Drug Indications Thrombolytic Agents Drug Class protein FDA Approval not approved by the FDA

Publications:

TTD: Anistreplase

Alternate Names: D0K4DI TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL2108250

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
17016423 17139284 6750837 7798503

Sources:
TdgClinicalTrial

Interaction Types & Directionality:

activator (activating)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
19436656 18673235 11752352 17963464

Sources:
TdgClinicalTrial TEND TTD

Alternate Names:

ANISTREPLASE Primary Drug Name

Drug Info:

Drug Class thrombolytic agents

Year of Approval not approved by the fda

Drug Info:

Drug Indications Thrombolytic Agents

Drug Class protein

FDA Approval not approved by the FDA

Alternate Names:

D0K4DI TTD Drug ID