DGIdb - APRINDINE Drug Record

APRINDINE chembl:CHEMBL1213033

Alternate Names:

APRINDINE
COMPOUND 99170
APRINDINA
SID50112831
SID90340712
APRINDINUM
pubchem.compound:2218
drugbank:01429
chembl:CHEMBL1213033
chemidplus:37640-71-4
rxcui:1054

Drug Info:

FDA Approval	not approved by the FDA
Drug Class	small molecule
Drug Indications	Anti-Arrhythmia Agents
Year of Approval	not approved by the fda
Drug Class	anti-arrhythmia agents

(0 More Sources)

Publications:

Kamiya et al., 1991, A combination of inactivated sodium channel blockers causes competitive interaction on dV/dtmax of single ventricular myocytes., Cardiovasc. Res.
Sato et al., 1991, Aprindine blocks the sodium current in guinea-pig ventricular myocytes., Naunyn Schmiedebergs Arch. Pharmacol.
Levine et al., Aprindine inhibits calmodulin-stimulated phosphodiesterase and Ca-ATPase activities., J. Cardiovasc. Pharmacol.

APRINDINE CALM1

Interaction Score: 20.61

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
6186851

Sources:
TEND
APRINDINE SCN5A

Interaction Score: 1.09

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1653644 1660104

Sources:
TdgClinicalTrial

TEND: APRINDINE
- Version: 01-August-2011
Alternate Names:

APRINDINE Primary Drug Name

Drug Info:

Drug Class anti-arrhythmia agents

Year of Approval not approved by the fda

Publications:
TdgClinicalTrial: APRINDINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anti-Arrhythmia Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Publications:
TTD: Aprindine
- Version: 2020.06.01
Alternate Names:

D0W7OE TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1213033
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

APRINDINE Drug Record

APRINDINE chembl:CHEMBL1213033

Alternate Names:

Drug Info:

Publications:

APRINDINE CALM1

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

PMIDs: 6186851

Sources: TEND

APRINDINE SCN5A

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 1653644 1660104

Sources: TdgClinicalTrial

TEND: APRINDINE

Alternate Names: APRINDINE Primary Drug Name

Drug Info: Drug Class anti-arrhythmia agents Year of Approval not approved by the fda

Publications:

TdgClinicalTrial: APRINDINE

Alternate Names:

Drug Info: Drug Indications Anti-Arrhythmia Agents Drug Class small molecule FDA Approval not approved by the FDA

Publications:

TTD: Aprindine

Alternate Names: D0W7OE TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1213033

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
6186851

Sources:
TEND

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1653644 1660104

Sources:
TdgClinicalTrial

Alternate Names:

APRINDINE Primary Drug Name

Drug Info:

Drug Class anti-arrhythmia agents

Year of Approval not approved by the fda

Drug Info:

Drug Indications Anti-Arrhythmia Agents

Drug Class small molecule

FDA Approval not approved by the FDA

Alternate Names:

D0W7OE TTD Drug ID