DGIdb - CLOCORTOLONE Drug Record

CLOCORTOLONE wikidata:Q5134843 Immunotherapy

Alternate Names:

CLOCORTOLON
CLOCORTOLONUM
CLOCORTOLONA
9-CHLORO-6ALPHA-FLUORO-11BETA,21-DIHYDROXY-16ALPHA-METHYL-1,4-PREGNADIEN-3,20-DIONE
9-CHLORO-6ALPHA-FLUORO-16ALPHA-METHYL-1,4-PREGNADIENE-11BETA,21-DIOL-3,20-DIONE
pubchem.compound:5311052
rxcui:21249
drugbank:00838
chemidplus:4828-27-7

Drug Info:

FDA Approval	1977
Drug Class	small molecule
Drug Indications	Corticosteroids, topical
Drug Indications	Anti-pruritics
Drug Indications	Anti-Inflammatory Agents
Drug Class	anti-inflammatory agents
Drug Class	anti-pruritics
Drug Class	corticosteroids, topical
Year of Approval	1977

(0 More Sources)

Publications:

Tanigawa et al., 2002, Species-specific differences in the glucocorticoid receptor transactivation function upon binding with betamethasone-esters., Int. Immunopharmacol.
Buchwald, 2008, Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model., Steroids
Ali et al., 2008, Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat., Bioorg. Med. Chem.

CLOCORTOLONE ANXA1

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TEND
CLOCORTOLONE PLA2G1B

Interaction Score: 0.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
CLOCORTOLONE NR3C1

Interaction Score: 0.64

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
12188035 18022656 18691892

Sources:
TdgClinicalTrial

TEND: CLOCORTOLONE
- Version: 01-August-2011
Alternate Names:

CLOCORTOLONE Primary Drug Name

Drug Info:

Year of Approval 1977

Drug Class corticosteroids, topical

Drug Class anti-pruritics

Publications:
TdgClinicalTrial: CLOCORTOLONE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Anti-Inflammatory Agents

Drug Indications Anti-pruritics

Drug Indications Corticosteroids, topical

Publications:
TTD: Clocortolone
- Version: 2020.06.01
Alternate Names:

D00GOS TTD Drug ID

Drug Info:

Publications:
Wikidata: wikidata:Q5134843
- Version: 12-August-2020
Alternate Names:

Drug Info:

Publications:

CLOCORTOLONE Drug Record

CLOCORTOLONE wikidata:Q5134843 Immunotherapy

Alternate Names:

Drug Info:

Publications:

CLOCORTOLONE ANXA1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TEND

CLOCORTOLONE PLA2G1B

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD

CLOCORTOLONE NR3C1

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
12188035 18022656 18691892

Sources:
TdgClinicalTrial

TEND: CLOCORTOLONE

Alternate Names:

CLOCORTOLONE Primary Drug Name

Drug Info:

Year of Approval 1977

Drug Class corticosteroids, topical

Drug Class anti-pruritics

Publications:

TdgClinicalTrial: CLOCORTOLONE

Alternate Names:

Drug Info:

Drug Indications Anti-Inflammatory Agents

Drug Indications Anti-pruritics

Drug Indications Corticosteroids, topical

Publications:

TTD: Clocortolone

Alternate Names:

D00GOS TTD Drug ID

Drug Info:

Publications:

Wikidata: wikidata:Q5134843

Alternate Names:

Drug Info:

Publications:

CLOCORTOLONE Drug Record

CLOCORTOLONE wikidata:Q5134843 Immunotherapy

Alternate Names:

Drug Info:

Publications:

CLOCORTOLONE ANXA1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TEND

CLOCORTOLONE PLA2G1B

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

CLOCORTOLONE NR3C1

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 12188035 18022656 18691892

Sources: TdgClinicalTrial

TEND: CLOCORTOLONE

Alternate Names: CLOCORTOLONE Primary Drug Name

Drug Info: Year of Approval 1977 Drug Class corticosteroids, topical Drug Class anti-pruritics

Publications:

TdgClinicalTrial: CLOCORTOLONE

Alternate Names:

Drug Info: Drug Indications Anti-Inflammatory Agents Drug Indications Anti-pruritics Drug Indications Corticosteroids, topical

Publications:

TTD: Clocortolone

Alternate Names: D00GOS TTD Drug ID

Drug Info:

Publications:

Wikidata: wikidata:Q5134843

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
12188035 18022656 18691892

Sources:
TdgClinicalTrial

Alternate Names:

CLOCORTOLONE Primary Drug Name

Drug Info:

Year of Approval 1977

Drug Class corticosteroids, topical

Drug Class anti-pruritics

Drug Info:

Drug Indications Anti-Inflammatory Agents

Drug Indications Anti-pruritics

Drug Indications Corticosteroids, topical

Alternate Names:

D00GOS TTD Drug ID