DGIdb - FLIBANSERIN Drug Record

FLIBANSERIN chembl:CHEMBL231068 Approved

Alternate Names:

FLIBANSERIN
ADDYI
BIMT-17
BIMT-17-BS
1-(2-(4-ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)-1-(PIPERAZINYL)ETHYL)-2-BENZIMIDAZOLINONE
BIMT 17
FEMALE VIAGRA (STREET NAME)
GIROSA® (PROPOSED TRADE NAME)
1,3-DIHYDRO-1-(2-(4-(3-(TRIFLUOROMETHYL)PHENYL)-1-PIPERAZINYL)ETHYL)-2H-BENZIMIDAZOL-2-ONE
ADDYI®
BIMT 17 BS
drugbank:04908
pubchem.compound:6918248
rxcui:1665509
chembl:CHEMBL231068
chemidplus:167933-07-5

Drug Info:

FDA Approval	not approved
Drug Class	Small molecule
Drug Indications	for treatment of female sexual dysfunction

(1 More Sources)

Publications:

Deeks, 2015, Flibanserin: First Global Approval., Drugs
Borsini et al., 2002, Pharmacology of flibanserin., CNS Drug Rev
Invernizzi et al., 2003, Flibanserin, a potential antidepressant drug, lowers 5-HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5-HT(1A) receptors., Br. J. Pharmacol.

FLIBANSERIN HTR1A

Interaction Score: 0.61

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name Flibanserin

PMIDs:
26412054 12177684 12890707

Sources:
TdgClinicalTrial TTD
FLIBANSERIN HTR2A

Interaction Score: 0.34

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name Flibanserin

Novel drug target Established target

PMIDs:
26412054 12177684 12890707

Sources:
TdgClinicalTrial TTD
FLIBANSERIN CYP2C8

Interaction Score: 0.27

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
FLIBANSERIN CYP2B6

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
FLIBANSERIN CYP2C9

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA
FLIBANSERIN CYP2C19

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA
FLIBANSERIN CYP2D6

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA
FLIBANSERIN CYP1A2

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
FLIBANSERIN CYP3A4

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

TdgClinicalTrial: FLIBANSERIN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications for treatment of female sexual dysfunction

Drug Class Small molecule

FDA Approval not approved

Publications:
TTD: Flibanserin
- Version: 2020.06.01
Alternate Names:

D0S9CB TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL231068
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
FDA: Flibanserin
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:
PharmGKB: flibanserin
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	Flibanserin

Trial Name	Flibanserin
Novel drug target	Established target

FLIBANSERIN Drug Record

FLIBANSERIN chembl:CHEMBL231068 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: agonist (activating)

Interaction Info: Novel drug target Established target Trial Name Flibanserin

PMIDs: 26412054 12177684 12890707

Sources: TdgClinicalTrial TTD

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name Flibanserin Novel drug target Established target

PMIDs: 26412054 12177684 12890707

Sources: TdgClinicalTrial TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

TdgClinicalTrial: FLIBANSERIN

Alternate Names:

Drug Info: Drug Indications for treatment of female sexual dysfunction Drug Class Small molecule FDA Approval not approved

Publications:

TTD: Flibanserin

Alternate Names: D0S9CB TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL231068

Alternate Names:

Drug Info:

Publications:

FDA: Flibanserin

Alternate Names:

Drug Info:

Publications:

PharmGKB: flibanserin

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Novel drug target Established target

Trial Name Flibanserin

PMIDs:
26412054 12177684 12890707

Sources:
TdgClinicalTrial TTD

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name Flibanserin

Novel drug target Established target

PMIDs:
26412054 12177684 12890707

Sources:
TdgClinicalTrial TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Drug Info:

Drug Indications for treatment of female sexual dysfunction

Drug Class Small molecule

FDA Approval not approved

Alternate Names:

D0S9CB TTD Drug ID