DGIdb - FOSPHENYTOIN Drug Record

FOSPHENYTOIN chembl:CHEMBL1201336 Approved

Alternate Names:

FOSPHENYTOIN
FOSFENITOINA
CEREBYX®
(3-PHOSPHORYLOXYMETHYL)PHENYTOIN
ACC-9653-010
FOSPHENYTOINE
FOSPHENYTOINUM
CI-982
drugbank:01320
chemidplus:93390-81-9
rxcui:72236
chembl:CHEMBL1201336
pubchem.compound:56339

Drug Info:

Year of Approval	1996
Drug Class	anticonvulsants
FDA Approval	approved
Drug Class	Small Molecule
Drug Indications	anticonvulsant

(2 More Sources)

Publications:

Swadron et al., 2004, A comparison of phenytoin-loading techniques in the emergency department., Acad Emerg Med
Mantegazza et al., 2010, Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders., Lancet Neurol
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Lenkowski et al., 2004, Block of human NaV1.5 sodium channels by novel alpha-hydroxyphenylamide analogues of phenytoin., Eur J Pharm Sci

FOSPHENYTOIN SCN5A

Interaction Score: 2.55

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name fosphenytoin sodium injection,Cerebyx

PMIDs:
15001403 20298965 11752352 15066664

Sources:
TdgClinicalTrial TEND TTD
FOSPHENYTOIN HLA-B

Interaction Score: 2.47

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA

TEND: FOSPHENYTOIN
- Version: 01-August-2011
Alternate Names:

FOSPHENYTOIN Primary Drug Name

Drug Info:

Drug Class anticonvulsants

Year of Approval 1996

Publications:
TdgClinicalTrial: FOSPHENYTOIN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications anticonvulsant

Drug Class Small Molecule

FDA Approval approved

Publications:
TTD: Fosphenytoin
- Version: 2020.06.01
Alternate Names:

D0J5YC TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1201336
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:
PharmGKB: fosphenytoin
- Version: 18-August-2020
Alternate Names:

Drug Info:

Publications:
FDA: Fosphenytoin
- Version: 04-September-2020
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	fosphenytoin sodium injection,Cerebyx

FOSPHENYTOIN Drug Record

FOSPHENYTOIN chembl:CHEMBL1201336 Approved

Alternate Names:

Drug Info:

Publications:

FOSPHENYTOIN SCN5A

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Novel drug target Established target Trial Name fosphenytoin sodium injection,Cerebyx

PMIDs: 15001403 20298965 11752352 15066664

Sources: TdgClinicalTrial TEND TTD

FOSPHENYTOIN HLA-B

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

TEND: FOSPHENYTOIN

Alternate Names: FOSPHENYTOIN Primary Drug Name

Drug Info: Drug Class anticonvulsants Year of Approval 1996

Publications:

TdgClinicalTrial: FOSPHENYTOIN

Alternate Names:

Drug Info: Drug Indications anticonvulsant Drug Class Small Molecule FDA Approval approved

Publications:

TTD: Fosphenytoin

Alternate Names: D0J5YC TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1201336

Alternate Names:

Drug Info:

Publications:

PharmGKB: fosphenytoin

Alternate Names:

Drug Info:

Publications:

FDA: Fosphenytoin

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name fosphenytoin sodium injection,Cerebyx

PMIDs:
15001403 20298965 11752352 15066664

Sources:
TdgClinicalTrial TEND TTD

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Alternate Names:

FOSPHENYTOIN Primary Drug Name

Drug Info:

Drug Class anticonvulsants

Year of Approval 1996

Drug Info:

Drug Indications anticonvulsant

Drug Class Small Molecule

FDA Approval approved

Alternate Names:

D0J5YC TTD Drug ID