DGIdb - IOBENGUANE Drug Record

IOBENGUANE chembl:CHEMBL818 Approved

Alternate Names:

IOBENGUANE
SID11111341
MIBG
ADREVIEW
M-IODOBENZYLGUANIDINE
METAIODOBENZYLGUANIDINE
SID90341658
3-IODOBENZYLGUANIDINE
((3-IODOPHENYL)METHYL)GUANIDINE
pubchem.compound:60860
chemidplus:80663-95-2
drugbank:06704
rxcui:14448
chembl:CHEMBL818

Drug Info:

(0 More Sources)

Publications:

Lode et al., 1995, Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression., Eur. J. Cancer
Hampel T et al., 2014, Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells., Bioorg Med Chem Lett

IOBENGUANE TH

Interaction Score: 2.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7576974

Sources:
NCI
IOBENGUANE SLC6A2

Interaction Score: 0.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24814532

Sources:
DTC
IOBENGUANE CYP2D6

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IOBENGUANE NFE2L2

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

NCI: MIBG

Version: 14-September-2017

Alternate Names:

C970 NCI drug code

Drug Info:

Publications:

Lode et al., 1995, Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression., Eur. J. Cancer

DTC: IOBENGUANE
- Version: 02-September-2020
Alternate Names:

CHEMBL818 ChEMBL Drug ID

Drug Info:

Publications:

Hampel T et al., 2014, Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells., Bioorg Med Chem Lett
ChemblDrugs: chembl:CHEMBL818
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

IOBENGUANE Drug Record

IOBENGUANE chembl:CHEMBL818 Approved

Alternate Names:

Drug Info:

Publications:

IOBENGUANE TH

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7576974

Sources:
NCI

IOBENGUANE SLC6A2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24814532

Sources:
DTC

IOBENGUANE CYP2D6

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

IOBENGUANE NFE2L2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

NCI: MIBG

Alternate Names:

C970 NCI drug code

Drug Info:

Publications:

Lode et al., 1995, Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression., Eur. J. Cancer

DTC: IOBENGUANE

Alternate Names:

CHEMBL818 ChEMBL Drug ID

Drug Info:

Publications:

Hampel T et al., 2014, Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells., Bioorg Med Chem Lett

ChemblDrugs: chembl:CHEMBL818

Alternate Names:

Drug Info:

Publications:

IOBENGUANE Drug Record

IOBENGUANE chembl:CHEMBL818 Approved

Alternate Names:

Drug Info:

Publications:

IOBENGUANE TH

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7576974

Sources: NCI

IOBENGUANE SLC6A2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24814532

Sources: DTC

IOBENGUANE CYP2D6

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

IOBENGUANE NFE2L2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

NCI: MIBG

Alternate Names: C970 NCI drug code

Drug Info:

Publications: Lode et al., 1995, Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression., Eur. J. Cancer

DTC: IOBENGUANE

Alternate Names: CHEMBL818 ChEMBL Drug ID

Drug Info:

Publications: Hampel T et al., 2014, Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells., Bioorg Med Chem Lett

ChemblDrugs: chembl:CHEMBL818

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
7576974

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
24814532

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

C970 NCI drug code

Publications:

Lode et al., 1995, Reverse transcriptase-polymerase chain reaction (RT-PCR) analysis of monoamine transporters in neuroblastoma cell lines: correlations to meta-iodobenzylguanidine (MIBG) uptake and tyrosine hydroxylase gene expression., Eur. J. Cancer

Alternate Names:

CHEMBL818 ChEMBL Drug ID

Publications:

Hampel T et al., 2014, Synthesis and biological effects of new hybrid compounds composed of benzylguanidines and the alkylating group of busulfan on neuroblastoma cells., Bioorg Med Chem Lett