DGIdb - OXYPHENCYCLIMINE Drug Record

OXYPHENCYCLIMINE chembl:CHEMBL1495 Approved

Alternate Names:

OXYPHENCYCLIMINE
OXIFENCICLIMINUM
OXYPHENCYCLIMINUM
pubchem.compound:4642
rxcui:32698
chemidplus:125-53-1
drugbank:00383
chembl:CHEMBL1495

Drug Info:

Drug Class	antispasmodics
Drug Class	gi anti-ulcer agents, anticholinergic
Year of Approval	approved before 1982
FDA Approval	Approved before 1982
Drug Class	small molecule
Drug Indications	Antispasmodics
Drug Indications	GI Anti-Ulcer Agents, anticholinergic

(0 More Sources)

Publications:

Waelbroeck et al., 1992, Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors., Eur. J. Pharmacol.
Schjelderup et al., 1988, Antimuscarinic effects of (R)- and (S)- oxyphencyclimine hydrochloride., Pharm. Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

OXYPHENCYCLIMINE CHRM2

Interaction Score: 1.82

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND
OXYPHENCYCLIMINE CHRM3

Interaction Score: 1.32

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND
OXYPHENCYCLIMINE CHRM1

Interaction Score: 1.1

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND
OXYPHENCYCLIMINE CHRM5

Interaction Score: 0.38

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD

TEND: OXYPHENCYCLIMINE
- Version: 01-August-2011
Alternate Names:

OXYPHENCYCLIMINE Primary Drug Name

Drug Info:

Year of Approval approved before 1982

Drug Class gi anti-ulcer agents, anticholinergic

Drug Class antispasmodics

Publications:
TdgClinicalTrial: OXYPHENCYCLIMINE
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications GI Anti-Ulcer Agents, anticholinergic

Drug Indications Antispasmodics

Drug Class small molecule

Publications:
TTD: Oxyphencyclimine
- Version: 2020.06.01
Alternate Names:

D0H5DU TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1495
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Trial Name	-
Novel drug target	Established target

Novel drug target	Established target
Trial Name	-

Trial Name	-
Novel drug target	Established target

OXYPHENCYCLIMINE Drug Record

OXYPHENCYCLIMINE chembl:CHEMBL1495 Approved

Alternate Names:

Drug Info:

Publications:

OXYPHENCYCLIMINE CHRM2

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 1426023 3247303 17016423 17139284

Sources: TdgClinicalTrial TEND

OXYPHENCYCLIMINE CHRM3

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 1426023 3247303 17016423 17139284

Sources: TdgClinicalTrial TEND

OXYPHENCYCLIMINE CHRM1

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Trial Name - Novel drug target Established target

PMIDs: 1426023 3247303 17016423 17139284

Sources: TdgClinicalTrial TEND

OXYPHENCYCLIMINE CHRM5

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

TEND: OXYPHENCYCLIMINE

Alternate Names: OXYPHENCYCLIMINE Primary Drug Name

Drug Info: Year of Approval approved before 1982 Drug Class gi anti-ulcer agents, anticholinergic Drug Class antispasmodics

Publications:

TdgClinicalTrial: OXYPHENCYCLIMINE

Alternate Names:

Drug Info: Drug Indications GI Anti-Ulcer Agents, anticholinergic Drug Indications Antispasmodics Drug Class small molecule

Publications:

TTD: Oxyphencyclimine

Alternate Names: D0H5DU TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1495

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Trial Name -

Novel drug target Established target

PMIDs:
1426023 3247303 17016423 17139284

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Alternate Names:

OXYPHENCYCLIMINE Primary Drug Name

Drug Info:

Year of Approval approved before 1982

Drug Class gi anti-ulcer agents, anticholinergic

Drug Class antispasmodics

Drug Info:

Drug Indications GI Anti-Ulcer Agents, anticholinergic

Drug Indications Antispasmodics

Drug Class small molecule

Alternate Names:

D0H5DU TTD Drug ID