DGIdb - QUININE Drug Record

QUININE chembl:CHEMBL170 Approved

Alternate Names:

NSC-192949
QUININE
WR297608
GNF-PF-506
QUININE SULFATE
CHININUM
(R)-(6-METHOXYQUINOLIN-4-YL)((2S,4S,8R)-8-VINYLQUINUCLIDIN-2-YL)METHANOL
CHININE
CHININ
(R)-(-)-QUININE
(R)-(6-METHOXY-QUINOLIN-4-YL)-((2S,5S)-5-VINYL-1-AZA-BICYCLO[2.2.2]OCT-2-YL)-METHANOL
6'-METHOXYCINCHONIDINE
QUININA
(8S,9R)-QUININE
QUINATE®
(-)-QUININE
QUALAQUIN®
QUININE BISULPHATE
chembl:CHEMBL170
pubchem.compound:3034034
chemidplus:130-95-0
rxcui:9071
drugbank:00468

Drug Info:

(1 More Sources)

Publications:

Bygbjerg et al., 1987, Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes., Int. J. Immunopharmacol.
Dos Reis et al., 1988, Stage-specific distinctions in potassium channel blocker control of T-lymphocyte activation., Int. J. Immunopharmacol.
Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev
Tu et al., 1996, Inhibitory effects of quinidine and quinine on liver microsome oxidation enzymes in man and rat., Zhongguo Yao Li Xue Bao
Dash S et al., 1977, Combined G-6PD and 6-PGD deficiency in a Hindu boy., Acta Haematol

QUININE COP1

Interaction Score: 1.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
QUININE CYP3A7

Interaction Score: 1.55

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9863152

Sources:
NCI
QUININE IL2

Interaction Score: 0.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
3497888 2846451

Sources:
NCI
QUININE G6PD

Interaction Score: 0.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
407765

Sources:
PharmGKB
QUININE THRB

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
QUININE ABCB1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
QUININE CYP3A4

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9187528

Sources:
PharmGKB
QUININE CYP2D6

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB

NCI: QUININE

Version: 14-September-2017

Alternate Names:

C794 NCI drug code

Drug Info:

Publications:

Bygbjerg et al., 1987, Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes., Int. J. Immunopharmacol.

Dos Reis et al., 1988, Stage-specific distinctions in potassium channel blocker control of T-lymphocyte activation., Int. J. Immunopharmacol.

Tu et al., 1996, Inhibitory effects of quinidine and quinine on liver microsome oxidation enzymes in man and rat., Zhongguo Yao Li Xue Bao

PharmGKB: quinine

Version: 18-August-2020

Alternate Names:

Drug Info:

Publications:

Dash S et al., 1977, Combined G-6PD and 6-PGD deficiency in a Hindu boy., Acta Haematol

Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

DTC: QUININE
- Version: 02-September-2020
Alternate Names:

CHEMBL387326 ChEMBL Drug ID

Drug Info:

Publications:
TTD: Quinine
- Version: 2020.06.01
Alternate Names:

D03DDR TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL170
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

QUININE Drug Record

QUININE chembl:CHEMBL170 Approved

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9863152

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 3497888 2846451

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 407765

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9187528

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

NCI: QUININE

Alternate Names: C794 NCI drug code

Drug Info:

PharmGKB: quinine

Alternate Names:

Drug Info:

Publications: Dash S et al., 1977, Combined G-6PD and 6-PGD deficiency in a Hindu boy., Acta Haematol Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

DTC: QUININE

Alternate Names: CHEMBL387326 ChEMBL Drug ID

Drug Info:

Publications:

TTD: Quinine

Alternate Names: D03DDR TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL170

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

n/a

PMIDs:
9863152

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
3497888 2846451

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
407765

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
9187528

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Alternate Names:

C794 NCI drug code

Publications:

Dash S et al., 1977, Combined G-6PD and 6-PGD deficiency in a Hindu boy., Acta Haematol

Rendic S et al., 1997, Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors., Drug Metab Rev

Alternate Names:

CHEMBL387326 ChEMBL Drug ID

Alternate Names:

D03DDR TTD Drug ID