DGIdb - TRIMETHAPHAN Drug Record

TRIMETHAPHAN chembl:CHEMBL1201329 Approved

Alternate Names:

TRIMETAPHAN
TRIMETHAPHAN

Drug Info:

Drug Class	vasodilator agents
Drug Class	antihypertensive agents
Year of Approval	approved before 1982
FDA Approval	Approved before 1982
Drug Class	small molecule
Drug Indications	Vasodilator Agents
Drug Indications	Antihypertensive Agents

(0 More Sources)

Publications:

Kurenny et al., 1994, Mechanism of long-lasting block of ganglion nicotinic receptors by mono-ammonium compounds with long aliphatic chain., J. Auton. Nerv. Syst.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Loiacono et al., 1993, Multiple binding sites for nicotine receptor antagonists in inhibiting [3H](-)-nicotine binding in rat cortex., Neuropharmacology

TRIMETHAPHAN CHRNA10

Interaction Score: 46.37

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
7963258 17016423 17139284 8232788

Sources:
TdgClinicalTrial TEND
TRIMETHAPHAN CHRNA4

Interaction Score: 0.81

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD

TEND: TRIMETHAPHAN
- Version: 01-August-2011
Alternate Names:

TRIMETHAPHAN Primary Drug Name

Drug Info:

Year of Approval approved before 1982

Drug Class antihypertensive agents

Drug Class vasodilator agents

Publications:
TdgClinicalTrial: TRIMETHAPHAN
- Version: January-2014
Alternate Names:

Drug Info:

Drug Indications Antihypertensive Agents

Drug Indications Vasodilator Agents

Drug Class small molecule

Publications:
TTD: Trimethaphan
- Version: 2020.06.01
Alternate Names:

D0B6CC TTD Drug ID

Drug Info:

Publications:
ChemblDrugs: chembl:CHEMBL1201329
- Version: ChEMBL_27
Alternate Names:

Drug Info:

Publications:

Novel drug target	Established target
Trial Name	-

TRIMETHAPHAN Drug Record

TRIMETHAPHAN chembl:CHEMBL1201329 Approved

Alternate Names:

Drug Info:

Publications:

TRIMETHAPHAN CHRNA10

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Novel drug target Established target Trial Name -

PMIDs: 7963258 17016423 17139284 8232788

Sources: TdgClinicalTrial TEND

TRIMETHAPHAN CHRNA4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

TEND: TRIMETHAPHAN

Alternate Names: TRIMETHAPHAN Primary Drug Name

Drug Info: Year of Approval approved before 1982 Drug Class antihypertensive agents Drug Class vasodilator agents

Publications:

TdgClinicalTrial: TRIMETHAPHAN

Alternate Names:

Drug Info: Drug Indications Antihypertensive Agents Drug Indications Vasodilator Agents Drug Class small molecule

Publications:

TTD: Trimethaphan

Alternate Names: D0B6CC TTD Drug ID

Drug Info:

Publications:

ChemblDrugs: chembl:CHEMBL1201329

Alternate Names:

Drug Info:

Publications:

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Novel drug target Established target

Trial Name -

PMIDs:
7963258 17016423 17139284 8232788

Sources:
TdgClinicalTrial TEND

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Alternate Names:

TRIMETHAPHAN Primary Drug Name

Drug Info:

Year of Approval approved before 1982

Drug Class antihypertensive agents

Drug Class vasodilator agents

Drug Info:

Drug Indications Antihypertensive Agents

Drug Indications Vasodilator Agents

Drug Class small molecule

Alternate Names:

D0B6CC TTD Drug ID