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ATP4A 495 Druggable Genome
Alternate Names:
495 ATPASE H+/K+ TRANSPORTING ALPHA SUBUNIT ATP4A ATP6A 137216 819 ENSG00000105675 OTTHUMG00000048106 P20648 ATP4A_HUMAN Gastric H(+)/K(+) ATPase subunit alpha Potassium-transporting ATPase alpha chain 1 Proton pump POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 (EC 3.6.3.10) (PROTON PUMP) (GASTRIC H+/K+ ATPASE ALPHA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P20648] Gastric H(+)/K(+) ATPase alpha T51666 Gastric H(+)/K(+) ATPase T92687 ATPase H+/K+ transporting subunit alpha Gene Info:
Target Subclass Active_transporters Target Main Class Transporters Target Subclass P-ATPase Transmembrane Helix Count 8 Interpro Acc IPR004014 Uniprot Evidence 2: Evidence at transcript level Interpro Short Name ATPase_P-typ_cation-exchng_asu Human Readable Name TRANSPORTER Interpro Type Domain Interpro Short Name ATPase_P-typ_cation-transptr_N Interpro Acc IPR006068 Interpro Name ATPase, P-type cation-transporter, C-terminal Interpro Type Family Uniprot Status Swiss-Prot Interpro Name ATPase, P-type cation-transporter, N-terminal Human Readable Name DRUGGABLE GENOME Interpro Short Name ATPase_P-typ_cation-transptr_C Interpro Acc IPR006069 Human Readable Name ION CHANNEL Interpro Name ATPase, P-type cation exchange, alpha subunit Target Class Transporters Target Subclass TC:3.A.3.1.2 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
TRANSPORTER ION CHANNEL DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 4.42
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Interaction Score: 4.42
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Interaction Score: 4.42
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name TAK-390MR, dexlansoprazole,Dexilant, Kapidex Novel drug target Established target Mechanism of Interaction Potassium-transporting ATPase inhibitor -
Interaction Score: 4.42
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Interaction Score: 3.43
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Interaction Score: 2.21
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Potassium-transporting ATPase inhibitor Direct Interaction yes -
Interaction Score: 2.21
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Potassium-transporting ATPase inhibitor Direct Interaction yes -
Interaction Score: 2.21
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Interaction Score: 2.21
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Potassium-transporting ATPase inhibitor -
Interaction Score: 1.61
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name CGT-2168 Novel drug target Established target Mechanism of Interaction Potassium-transporting ATPase inhibitor -
Interaction Score: 1.47
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Potassium-transporting ATPase inhibitor -
Interaction Score: 1.1
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Potassium-transporting ATPase inhibitor Direct Interaction yes -
Interaction Score: 1.02
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Potassium-transporting ATPase inhibitor Direct Interaction yes Trial Name lansoprazole , AG 1749,Prevacid, Takepron -
Interaction Score: 0.26
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Potassium-transporting ATPase inhibitor Direct Interaction yes
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- Version: 101_38
Alternate Names:
ATP4A Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
ATP4A Uniprot Gene Name POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 Uniprot Protein Name P20648 Uniprot Accession Gene Info:
Uniprot Evidence 2: Evidence at transcript level Interpro Short Name ATPase_P-typ_cation-exchng_asu Human Readable Name TRANSPORTER Gene Categories:
TRANSPORTER, ION CHANNEL, DRUGGABLE GENOME Publications:
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Alternate Names:
ATP4A_HUMAN Uniprot Id ATP4A Gene Symbol 495 Entrez Gene Id Gene Info:
Target Subclass Active_transporters Target Main Class Transporters Target Subclass P-ATPase Publications:
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- Version: January-2014
Alternate Names:
ATP4A Gene Symbol Gene Info:
Target Class Transporters Target Subclass TC:3.A.3.1.2 Publications:
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- Version: 26-July-2011
Alternate Names:
ATP4A Display Id ENSG00000105675 Ensembl Gene Id POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 (EC 3.6.3.10) (PROTON PUMP) (GASTRIC H+/K+ ATPASE ALPHA SUBUNIT). [SOURCE:UNIPROT/SWISSPROT;ACC:P20648] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
ATP4A GENE_SYMBOL Potassium-transporting ATPase alpha chain 1 UNIPROT Gastric H(+)/K(+) ATPase subunit alpha UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000105675 Gene Symbol ATP4A Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 2020.06.01
Alternate Names:
ATP4A TTD Gene Abbreviation T51666 TTD Target ID Gene Info:
Publications:
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- Version: 2020.06.01
Alternate Names:
Proton pump TTD Gene Abbreviation T92687 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Potassium-transporting ATPase alpha chain 1 Gene Name P20648 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: