DGIdb - CYP27A1 Gene Record

CYP27A1 1593 Druggable Genome

Alternate Names:

1593
CYTOCHROME P450 FAMILY 27 SUBFAMILY A MEMBER 1
CYP27A1
CP27
CTX
CYP27
606530
2605
ENSG00000135929
OTTHUMG00000048238
Q02318
STEROL 26-HYDROXYLASE, MITOCHONDRIAL
CP27A_HUMAN
CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (CYTOCHROME P-450C27/25) (STEROL 26-HYDROXYLASE) (STEROL 27-HYDROXYLASE) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE). [SOURCE:UNIPROT/SWISSPROT;A
PA135

Gene Info:

Interpro Short Name	Cyt_P450
Interpro Acc	IPR001128
Uniprot Evidence	1: Evidence at protein level
Human Readable Name	DRUGGABLE GENOME
Interpro Type	Family
Human Readable Name	CYTOCHROME P450
Uniprot Status	Swiss-Prot
Interpro Name	Cytochrome P450
Gene Biotype	PROTEIN_CODING

(4 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
CYTOCHROME P450
ENZYME

Publications:

Björkhem et al., 2002, Differences in the regulation of the classical and the alternative pathway for bile acid synthesis in human liver. No coordinate regulation of CYP7A1 and CYP27A1., J. Biol. Chem.

CHOLESTYRAMINE CYP27A1

Interaction Score: 41.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12011083

Sources:
NCI

Ensembl: ENSG00000135929
- Version: 101_38
Alternate Names:

CYP27A1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: Q02318
- Version: 11-September-2012
Alternate Names:

STEROL 26-HYDROXYLASE, MITOCHONDRIAL Uniprot Protein Name

CP27A_HUMAN Uniprot Id

CYP27A1 Uniprot Gene Name

Gene Info:

Interpro Acc IPR001128

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME, CYTOCHROME P450

Publications:

RussLampel: ENSG00000135929

Version: 26-July-2011

Alternate Names:

CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (CYTOCHROME P-450C27/25) (STEROL 26-HYDROXYLASE) (STEROL 27-HYDROXYLASE) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE). [SOURCE:UNIPROT/SWISSPROT;A Description

CYP27A1 Display Id

ENSG00000135929 Ensembl Gene Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

NCI: CYP27A1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Araya et al., 2003, Hormonal regulation of the human sterol 27-hydroxylase gene CYP27A1., Biochem. J.

Moghadasian et al., 2001, Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment., Metab. Clin. Exp.

Szanto et al., 2004, Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages., Mol. Cell. Biol.

HingoraniCasas: ENSG00000135929
- Version: 31-May-2017
Alternate Names:

ENSG00000135929 Gene Symbol

CYP27A1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
PharmGKB: CYP27A1
- Version: 18-August-2020
Alternate Names:

PA135 PharmGKB ID

Gene Info:

Publications:
HumanProteinAtlas: CYP27A1
- Version: 19.3
Alternate Names:

ENSG00000135929 Ensembl Gene ID

CP27 Human Protein Atlas Gene Synonym

CTX Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories:

ENZYME

Publications:
Pharos: CYP27A1
- Version: 01-February-2022
Alternate Names:

Sterol 26-hydroxylase, mitochondrial Gene Name

Q02318 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

STEROL 26-HYDROXYLASE, MITOCHONDRIAL	Uniprot Protein Name
CP27A_HUMAN	Uniprot Id
CYP27A1	Uniprot Gene Name

CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR (EC 1.14.-.-) (CYTOCHROME P-450C27/25) (STEROL 26-HYDROXYLASE) (STEROL 27-HYDROXYLASE) (VITAMIN D(3) 25-HYDROXYLASE) (5-BETA-CHOLESTANE-3-ALPHA,7-ALPHA,12-ALPHA-TRIOL 27-HYDROXYLASE). [SOURCE:UNIPROT/SWISSPROT;A	Description
CYP27A1	Display Id
ENSG00000135929	Ensembl Gene Id

Sterol 26-hydroxylase, mitochondrial	Gene Name
Q02318	UniProt ID

CYP27A1 Gene Record

CYP27A1 1593 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

CHOLESTYRAMINE CYP27A1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12011083

Sources: NCI

Ensembl: ENSG00000135929

Alternate Names: CYP27A1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: Q02318

Alternate Names: STEROL 26-HYDROXYLASE, MITOCHONDRIAL Uniprot Protein Name CP27A_HUMAN Uniprot Id CYP27A1 Uniprot Gene Name

Gene Info: Interpro Acc IPR001128 Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME, CYTOCHROME P450

Publications:

RussLampel: ENSG00000135929

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

NCI: CYP27A1

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000135929

Alternate Names: ENSG00000135929 Gene Symbol CYP27A1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

PharmGKB: CYP27A1

Alternate Names: PA135 PharmGKB ID

Gene Info:

Publications:

HumanProteinAtlas: CYP27A1

Alternate Names: ENSG00000135929 Ensembl Gene ID CP27 Human Protein Atlas Gene Synonym CTX Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories: ENZYME

Publications:

Pharos: CYP27A1

Alternate Names: Sterol 26-hydroxylase, mitochondrial Gene Name Q02318 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
12011083

Sources:
NCI

Alternate Names:

CYP27A1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

STEROL 26-HYDROXYLASE, MITOCHONDRIAL Uniprot Protein Name

CP27A_HUMAN Uniprot Id

CYP27A1 Uniprot Gene Name

Gene Info:

Interpro Acc IPR001128

Uniprot Evidence 1: Evidence at protein level

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME, CYTOCHROME P450

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000135929 Gene Symbol

CYP27A1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

PA135 PharmGKB ID

Alternate Names:

ENSG00000135929 Ensembl Gene ID

CP27 Human Protein Atlas Gene Synonym

CTX Human Protein Atlas Gene Synonym

Gene Categories:

ENZYME

Alternate Names:

Sterol 26-hydroxylase, mitochondrial Gene Name

Q02318 UniProt ID

Gene Categories:

ENZYME