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F10 2159 Druggable Genome
Alternate Names:
2159 COAGULATION FACTOR X F10 FX FXA 613872 3528 ENSG00000126218 OTTHUMG00000017374 P00742 FA10_HUMAN Activated factor Xa heavy chain Factor X light chain Factor X heavy chain Stuart factor Stuart-Prower factor COAGULATION FACTOR XA COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) (STUART- PROWER FACTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P00742] T84631 Gene Info:
Uniprot Status Swiss-Prot Interpro Short Name Peptidase_S1_S6 Human Readable Name DRUGGABLE GENOME Uniprot Evidence 1: Evidence at protein level Human Readable Name PROTEASE Interpro Name Peptidase S1/S6, chymotrypsin/Hap Interpro Type Domain Interpro Acc IPR001254 Target Class Enzymes Target Subclass EC:3.4.21.6 Target Main Class Enzymes Target Subclass 3.4.21.6 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
PROTEASE DRUGGABLE GENOME Publications:
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Interaction Score: 20.61
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name betrixaban, PRT054021, Factor Xa inhibitor Novel drug target Established target Mechanism of Interaction Coagulation factor X inhibitor -
Interaction Score: 8.83
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Interaction Score: 8.83
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Novel drug target Established target Trial Name otamixaban, XRP0673 -
Interaction Score: 7.85
Interaction Types & Directionality:
antagonist (inhibitory) inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Coagulation factor X inhibitor Trial Name rivaroxaban, BAY 59-7939,Xarelto -
Interaction Score: 5.89
-
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name TAK-442 Novel drug target Established target Mechanism of Interaction Coagulation factor X inhibitor -
Interaction Score: 5.89
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name LY-517717 Novel drug target Established target -
Interaction Score: 5.89
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Coagulation factor X inhibitor Direct Interaction yes -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name edoxaban, DU-176b Novel drug target Established target -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Coagulation factor X inhibitor Trial Name Apixaban -
Interaction Score: 2.94
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Interaction Score: 2.94
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name idraparinux, SanOrg 34006 Novel drug target Established target -
Interaction Score: 2.94
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Interaction Score: 2.94
-
Interaction Score: 2.94
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Coagulation factor X inhibitor -
Interaction Score: 1.47
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name tinzaparin sodium injection,Innohep Novel drug target Established target -
Interaction Score: 1.47
-
Interaction Score: 0.49
-
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name ProFibrix B.V/ Novel drug target Established target
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- Version: 101_38
Alternate Names:
F10 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
F10 Display Id COAGULATION FACTOR X PRECURSOR (EC 3.4.21.6) (STUART FACTOR) (STUART- PROWER FACTOR). [SOURCE:UNIPROT/SWISSPROT;ACC:P00742] Description ENSG00000126218 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
ENSG00000126218 Ensembl Gene Id 2159 Entrez Gene Id F10 Gene Symbol Gene Info:
Target Main Class Enzymes Target Subclass 3.4.21.6 Publications:
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- Version: January-2014
Alternate Names:
F10 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:3.4.21.6 Publications:
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- Version: 11-September-2012
Alternate Names:
ENSG00000126218 Ensembl Gene Id P00742 Uniprot Accession FA10_HUMAN Uniprot Id Gene Info:
Uniprot Status Swiss-Prot Interpro Short Name Peptidase_S1_S6 Human Readable Name DRUGGABLE GENOME Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
-
Alternate Names:
Gene Info:
Publications:
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- Version: chembl_23
Alternate Names:
F10 GENE_SYMBOL Coagulation factor X UNIPROT Factor X light chain UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000126218 Gene Symbol F10 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
-
Alternate Names:
2159 Gene ID FX dGene Synonym FXA dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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- Version: 2020.06.01
Alternate Names:
F10 TTD Gene Abbreviation T84631 TTD Target ID Gene Info:
Publications: