FGR Gene Record

  • FGR 2268 Druggable GenomeClinically Actionable

    Alternate Names:

    2268
    FGR PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE
    FGR
    SRC2
    c-fgr
    c-src2
    p55-Fgr
    p55c-fgr
    p58-Fgr
    p58c-fgr
    164940
    3697
    ENSG00000000938
    OTTHUMG00000003516
    Tyrosine-protein kinase Fgr
    Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
    Proto-oncogene c-Fgr
    PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FGR (EC 2.7.1.112) (P55-FGR) (C-FGR). [SOURCE:UNIPROT/SWISSPROT;ACC:P09769]
    P09769
    FGR_HUMAN

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Human Readable Name KINASE
    Interpro Acc IPR001245
    Initial Gene Query FGR
    Counted Citations from 1950-2000 304
    Gene Biotype PROTEIN_CODING
    (10 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

  • XL-228   FGR

    Interaction Score: 0.64

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • TG100-801   FGR

    Interaction Score: 0.64

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction SRC inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • NINTEDANIB   FGR

    Interaction Score: 0.49

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • ENMD-981693   FGR

    Interaction Score: 0.38

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • DASATINIB   FGR

    Interaction Score: 0.29

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    18180381


    Sources:
    ChemblInteractions

  • ILORASERTIB   FGR

    Interaction Score: 0.1

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • Ensembl: ENSG00000000938

    • Version: 101_38

    Alternate Names:
    FGR Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000000938

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000000938 Ensembl Gene Id
    FGR Display Id
    PROTO-ONCOGENE TYROSINE-PROTEIN KINASE FGR (EC 2.7.1.112) (P55-FGR) (C-FGR). [SOURCE:UNIPROT/SWISSPROT;ACC:P09769] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P09769

    • Version: 11-September-2012

    Alternate Names:
    P09769 Uniprot Accession
    2268 Entrez Gene Id
    TYROSINE-PROTEIN KINASE FGR Uniprot Protein Name

    Gene Info:
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • BaderLabGenes: FGR

    • Version: February-2014

    Alternate Names:
    2268 Entrez Gene ID

    Gene Info:
    Initial Gene Query FGR
    Counted Citations from 1950-2000 304

    Gene Categories:
    KINASE

    Publications:

  • NCI: FGR

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Vicentini et al., 2002, Fgr deficiency results in defective eosinophil recruitment to the lung during allergic airway inflammation., J. Immunol.

  • TALC: FGR

    • Version: 12-May-2016

    Alternate Names:
    FGR Gene Symbol

    Gene Info:

    Publications:

  • ChemblInteractions: SRC2

    • Version: chembl_23

    Alternate Names:
    SRC2 GENE_SYMBOL
    FGR GENE_SYMBOL
    Tyrosine-protein kinase Fgr UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000000938

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000000938 Gene Symbol
    FGR Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: FGR

    • Version: 19.3

    Alternate Names:
    ENSG00000000938 Ensembl Gene ID
    c-fgr Human Protein Atlas Gene Synonym
    p55c-fgr Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: FGR

    • Version: 01-February-2022

    Alternate Names:
    SRC2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications:

  • dGene: FGR

    • Version: 27-Jun-2013

    Alternate Names:
    2268 Gene ID
    SRC2 dGene Synonym
    c-fgr dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • Pharos: FGR

    • Version: 01-February-2022

    Alternate Names:
    Tyrosine-protein kinase Fgr Gene Name
    P09769 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • CarisMolecularIntelligence: FGR

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • Oncomine: FGR

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: