2550 |
GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 |
GABBR1 |
GABABR1 |
GABBR1-3 |
GB1 |
GPRC3A |
603540 |
4070 |
ENSG00000204681 |
OTTHUMG00000031095 |
Q9UBS5 |
GABA-B receptor 1 |
GABA-B-R1 |
GABA-BR1 |
GABR1_HUMAN |
ENSG00000197402 |
GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR, SUBUNIT 1 PRECURSOR (GABA-B RECEPTOR 1) (GABA-B-R1) (GB1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UBS5] |
ENSG00000204681; ENSG00000206466; ENSG00000206511; ENSG00000232632; ENSG00000237112; ENSG00000237051; ENSG00000232569 |
dJ271M21.1.1 |
dJ271M21.1.2 |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Glutamate |
Human Readable Name | DRUGGABLE GENOME |
Transmembrane Helix Count | 7 |
Target Main Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
agonist (activating) |
Novel drug target | Established target |
Trial Name | Arbaclofen |
Mechanism of Interaction | GABA-B receptor agonist |
agonist (activating) |
Trial Name | - |
Novel drug target | Established target |
agonist (activating) |
Trial Name | ALKS 29 |
Novel drug target | Established target |
Mechanism of Interaction | GABA-B receptor agonist |
agonist (activating) |
Mechanism of Interaction | GABA-B receptor 1 agonist |
Direct Interaction | yes |
Novel drug target | Established target |
agonist (activating) |
Trial Name | Vigabatrin is a selective, irreversible enzyme-activated GABA transaminase inhibitor. GABA (gamma-aminobutyric acid) is a n/ |
Novel drug target | Established target |
agonist (activating) |
Mechanism of Interaction | GABA-B receptor agonist |
Direct Interaction | yes |
GABBR1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ENSG00000197402 | Ensembl Gene Id |
GABBR1 | Display Id |
GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR, SUBUNIT 1 PRECURSOR (GABA-B RECEPTOR 1) (GABA-B-R1) (GB1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9UBS5] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
GABR1_HUMAN | Uniprot Id |
GABBR1 | Gene Symbol |
Q9UBS5 | Uniprot Accession |
Transmembrane Helix Count | 7 |
Target Subclass | GPCR |
Target Subclass | Glutamate |
GABBR1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Glutamate |
GPRC3A | GENE_SYMBOL |
GABBR1 | GENE_SYMBOL |
Gamma-aminobutyric acid type B receptor subunit 1 | UNIPROT |
ENSG00000204681 | Gene Symbol |
GABBR1 | Ensembl Id |
DRUGGABLE GENOME |
2550 | Gene ID |
GABABR1 | dGene Synonym |
GABBR1-3 | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |