GHR Gene Record

  • PEGVISOMANT   GHR

    Interaction Score: 98.93

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Growth hormone receptor antagonist
    Direct Interaction yes
    Trial Name pegvisomant,Somavert

    PMIDs:
    17322491 11752352 19820031 20595800


    Sources:
    TdgClinicalTrial ChemblInteractions TEND TTD

  • SOMATROGON   GHR

    Interaction Score: 12.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name MOD-4023, hGH-CTP
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • SOMATROPIN   GHR

    Interaction Score: 12.37

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Growth hormone receptor agonist
    Direct Interaction yes
    Trial Name ALTU-238, somatropin

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • SOMATREM   GHR

    Interaction Score: 12.37

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Mechanism of Interaction Growth hormone receptor agonist
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • ACP-001   GHR

    Interaction Score: 6.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name ACP-001

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Ensembl: ENSG00000112964

    • Version: 101_38

    Alternate Names:
    GHR Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TEND: P10912

    • Version: 01-August-2011

    Alternate Names:
    2690 Entrez Gene Id
    GHR Gene Symbol
    GHR_HUMAN Uniprot Id

    Gene Info:
    Target Main Class Receptors
    Transmembrane Helix Count 1
    Target Subclass IG

    Publications:

  • TdgClinicalTrial: P10912

    • Version: January-2014

    Alternate Names:
    GHR Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass Receptor
    Target Subclass Type 1 cytokine receptor

    Publications:

  • ChemblInteractions: GHR

    • Version: chembl_23

    Alternate Names:
    GHR GENE_SYMBOL
    Growth hormone receptor UNIPROT
    Growth hormone-binding protein UNIPROT

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000112964

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000112964 Gene Symbol
    GHR Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: Growth hormone receptor

    • Version: 2020.06.01

    Alternate Names:
    GHR TTD Gene Abbreviation
    T02333 TTD Target ID

    Gene Info:

    Publications:

  • GO: GHR

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    CELL SURFACE, EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications: