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GUCY2C 2984 Druggable Genome
Alternate Names:
2984 GUANYLATE CYCLASE 2C GUCY2C DIAR6 GC-C GUC2C MECIL MUCIL STAR 601330 4688 ENSG00000070019 OTTHUMG00000168732 P25092 Intestinal guanylate cyclase Heat-stable enterotoxin receptor Guanylyl cyclase C hSTAR STA receptor HEAT-STABLE ENTEROTOXIN RECEPTOR PRECURSOR (GC-C) (INTESTINAL GUANYLATE CYCLASE) (EC 4.6.1.2) (STA RECEPTOR) (HSTAR). [SOURCE:UNIPROT/SWISSPROT;ACC:P25092] GUC2C_HUMAN T97947 Gene Info:
Human Readable Name DRUGGABLE GENOME Target Class Receptors Target Subclass EC:4.6.1.2 Interpro Acc IPR001054 Interpro Short Name A/G_cyclase Interpro Type Domain Interpro Acc IPR001245 Uniprot Evidence 1: Evidence at protein level Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Uniprot Status Swiss-Prot Interpro Name Adenylyl cyclase class-3/4/guanylyl cyclase Human Readable Name KINASE Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE DRUGGABLE GENOME
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Interaction Score: 61.83
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Heat-stable enterotoxin receptor agonist Direct Interaction yes Trial Name Linaclotide -
Interaction Score: 46.37
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name plecanatide , SP-304 Novel drug target Novel Target Mechanism of Interaction Heat-stable enterotoxin receptor agonist -
Interaction Score: 15.46
Interaction Types & Directionality:
agonist (activating) Interaction Info:
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Interaction Score: 15.46
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- Version: 101_38
Alternate Names:
GUCY2C Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000070019 Ensembl Gene Id HEAT-STABLE ENTEROTOXIN RECEPTOR PRECURSOR (GC-C) (INTESTINAL GUANYLATE CYCLASE) (EC 4.6.1.2) (STA RECEPTOR) (HSTAR). [SOURCE:UNIPROT/SWISSPROT;ACC:P25092] Description GUCY2C Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
GUCY2C Uniprot Gene Name GUC2C_HUMAN Uniprot Id HEAT-STABLE ENTEROTOXIN RECEPTOR Uniprot Protein Name Gene Info:
Interpro Acc IPR001054 Interpro Short Name A/G_cyclase Interpro Type Domain Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
GUCY2C Gene Symbol Gene Info:
Target Class Receptors Target Subclass EC:4.6.1.2 Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000070019 Gene Symbol GUCY2C Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
STAR GENE_SYMBOL GUCY2C GENE_SYMBOL Heat-stable enterotoxin receptor UNIPROT Gene Info:
Publications:
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- Version: 2020.06.01
Alternate Names:
GUCY2C TTD Gene Abbreviation T97947 TTD Target ID Gene Info:
Publications: