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HCRTR2 3062 Druggable Genome
Alternate Names:
3062 HYPOCRETIN RECEPTOR 2 HCRTR2 OX2R 602393 4849 ENSG00000137252 OTTHUMG00000016150 Ox-2-R Hypocretin receptor type 2 Orexin receptor type 2 Ox2-R O43614 OX2R_HUMAN OREXIN RECEPTOR TYPE 2 (OX2R) (HYPOCRETIN RECEPTOR TYPE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:O43614] T69485 ORXR2 OXR2 Gene Info:
Human Readable Name DRUGGABLE GENOME Target Class Receptors Target Subclass GPCR Target Subclass Rhodopsin Human Readable Name G PROTEIN COUPLED RECEPTOR Uniprot Status Swiss-Prot Interpro Type Family Interpro Acc IPR000276 Uniprot Evidence 2: Evidence at transcript level Interpro Short Name 7TM_GPCR_Rhodpsn Interpro Name GPCR, rhodopsin-like, 7TM Gene Biotype PROTEIN_CODING Gene Categories: Category Details
G PROTEIN COUPLED RECEPTOR DRUGGABLE GENOME
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Interaction Score: 24.73
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Orexin receptor antagonist Direct Interaction yes Trial Name MK-4305 -
Interaction Score: 12.37
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
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Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Orexin receptor 2 antagonist Direct Interaction yes -
Interaction Score: 6.18
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Novel drug target Novel Target Trial Name almorexant, ACT-078573 -
Interaction Score: 6.18
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Mechanism of Interaction Orexin receptor 2 antagonist Direct Interaction yes
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- Version: 101_38
Alternate Names:
HCRTR2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
HCRTR2 Gene Symbol Gene Info:
Target Class Receptors Target Subclass GPCR Target Subclass Rhodopsin Publications:
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- Version: 26-July-2011
Alternate Names:
OREXIN RECEPTOR TYPE 2 (OX2R) (HYPOCRETIN RECEPTOR TYPE 2). [SOURCE:UNIPROT/SWISSPROT;ACC:O43614] Description ENSG00000137252 Ensembl Gene Id HCRTR2 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
3062 Entrez Gene Id OX2R_HUMAN Uniprot Id ENSG00000137252 Ensembl Gene Id Gene Info:
Uniprot Status Swiss-Prot Interpro Type Family Human Readable Name G PROTEIN COUPLED RECEPTOR Gene Categories:
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
HCRTR2 GENE_SYMBOL Orexin receptor type 2 UNIPROT Hypocretin receptor type 2 UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000137252 Gene Symbol HCRTR2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
3062 Gene ID OX2R dGene Synonym Gene Info:
Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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- Version: 2020.06.01
Alternate Names:
HCRTR2 TTD Gene Abbreviation T69485 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Gene Info:
Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications: