DGIdb - HERC2 Gene Record

HERC2 8924

Alternate Names:

8924
HECT AND RLD DOMAIN CONTAINING E3 UBIQUITIN PROTEIN LIGASE 2
HERC2
D15F37S1
MRT38
SHEP1
jdf2
p528
605837
4868
ENSG00000128731
OTTHUMG00000129251
O95714

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

DNA REPAIR
ENZYME

Publications:

Bose et al., 2013, Activating HER2 mutations in HER2 gene amplification negative breast cancer., Cancer Discov

NERATINIB HERC2

Interaction Score: 11.24

Interaction Types & Directionality:

n/a

Interaction Info:

Clinical Status preclinical

Pathway activation

Variant Effect gain-of-function

PMIDs:
23220880

Sources:
DoCM

Ensembl: ENSG00000128731
- Version: 101_38
Alternate Names:

HERC2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
DoCM: HERC2
- Version: 27-September-2017
Alternate Names:

Gene Info:

Publications:

Bose et al., 2013, Activating HER2 mutations in HER2 gene amplification negative breast cancer., Cancer Discov
HumanProteinAtlas: HERC2
- Version: 19.3
Alternate Names:

ENSG00000128731 Ensembl Gene ID

D15F37S1 Human Protein Atlas Gene Synonym

jdf2 Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories:

ENZYME

Publications:
GO: HERC2
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

DNA REPAIR

Publications:

Clinical Status	preclinical
Pathway	activation
Variant Effect	gain-of-function

ENSG00000128731	Ensembl Gene ID
D15F37S1	Human Protein Atlas Gene Synonym
jdf2	Human Protein Atlas Gene Synonym

HERC2 Gene Record

HERC2 8924

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

NERATINIB HERC2

Interaction Types & Directionality: n/a

Interaction Info: Clinical Status preclinical Pathway activation Variant Effect gain-of-function

PMIDs: 23220880

Sources: DoCM

Ensembl: ENSG00000128731

Alternate Names: HERC2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DoCM: HERC2

Alternate Names:

Gene Info:

Publications: Bose et al., 2013, Activating HER2 mutations in HER2 gene amplification negative breast cancer., Cancer Discov

HumanProteinAtlas: HERC2

Alternate Names: ENSG00000128731 Ensembl Gene ID D15F37S1 Human Protein Atlas Gene Synonym jdf2 Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories: ENZYME

Publications:

GO: HERC2

Alternate Names:

Gene Info:

Gene Categories: DNA REPAIR

Publications:

Interaction Types & Directionality:

n/a

Interaction Info:

Clinical Status preclinical

Pathway activation

Variant Effect gain-of-function

PMIDs:
23220880

Sources:
DoCM

Alternate Names:

HERC2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

Bose et al., 2013, Activating HER2 mutations in HER2 gene amplification negative breast cancer., Cancer Discov

Alternate Names:

ENSG00000128731 Ensembl Gene ID

D15F37S1 Human Protein Atlas Gene Synonym

jdf2 Human Protein Atlas Gene Synonym

Gene Categories:

ENZYME

Gene Categories:

DNA REPAIR