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ITGB5 3693 Druggable Genome
Alternate Names:
3693 INTEGRIN SUBUNIT BETA 5 ITGB5 147561 6160 ENSG00000082781 OTTHUMG00000159432 P18084 Integrin beta-5 ITB5_HUMAN INTEGRIN BETA-5 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18084] Gene Info:
Target Class Miscellaneous Target Subclass Receptor Target Subclass integrin Human Readable Name DRUGGABLE GENOME Interpro Type Domain Interpro Name Integrin beta subunit, N-terminal Uniprot Evidence 1: Evidence at protein level Interpro Acc IPR002369 Uniprot Status Swiss-Prot Interpro Short Name Integrin_bsu_N Gene Biotype PROTEIN_CODING Gene Categories: Category Details
CELL SURFACE DRUGGABLE GENOME Publications:
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Interaction Score: 9.27
Interaction Types & Directionality:
antagonist (inhibitory) inhibitor (inhibitory) Interaction Info:
Notes Targets ALPHA-V/BETA-3 INTEGRIN Trial Name cilengitide. EMD-121974 Novel drug target Novel Target -
Interaction Score: 6.18
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Trial Name CNTO-95 Novel drug target Novel Target Mechanism of Interaction Integrin alpha-V/beta-5 antagonist -
Interaction Score: 3.09
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Integrin alpha-V/beta-5 inhibitor Direct Interaction yes -
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name GLPG0187 Novel drug target Novel Target
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- Version: 101_38
Alternate Names:
ITGB5 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
ITGB5 Gene Symbol Gene Info:
Target Class Miscellaneous Target Subclass Receptor Target Subclass integrin Publications:
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- Version: 11-September-2012
Alternate Names:
ITB5_HUMAN Uniprot Id ITGB5 Uniprot Gene Name ENSG00000082781 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Interpro Type Domain Interpro Name Integrin beta subunit, N-terminal Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000082781 Ensembl Gene Id ITGB5 Display Id INTEGRIN BETA-5 PRECURSOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P18084] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
ITGB5 GENE_SYMBOL Integrin beta-5 UNIPROT Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000082781 Gene Symbol ITGB5 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
ITGB5 Gene Symbol Gene Info:
Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CELL SURFACE Publications: