3764 |
POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY J MEMBER 8 |
KCNJ8 |
KIR6.1 |
uKATP-1 |
600935 |
6269 |
ENSG00000121361 |
OTTHUMG00000169093 |
Potassium channel, inwardly rectifying subfamily J member 8 |
Inward rectifier K(+) channel Kir6.1 |
ATP-sensitive inward rectifier potassium channel 8 |
Q15842 |
IRK8_HUMAN |
ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 (POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 8) (INWARDLY RECTIFIER K(+) CHANNEL KIR6.1) (UKATP-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15842] |
potassium inwardly rectifying channel subfamily J member 8 |
Target Class | Transporters |
Target Subclass | TC:1.A.2.1 |
Target Main Class | Transporters |
Target Subclass | InwardlyRectifyingKchannel |
Target Subclass | Channels |
Transmembrane Helix Count | 2 |
Target Subclass | Voltage_gated_ion_channels |
Human Readable Name | DRUGGABLE GENOME |
Initial Gene Query | Kir6.1 |
Counted Citations from 1950-2000 | 247 |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
n/a |
Mechanism of Interaction | Sulfonylurea receptors; K-ATP channels opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Sulfonylurea receptors; K-ATP channels opener |
Direct Interaction | yes |
n/a |
Mechanism of Interaction | Potassium channel, inwardly rectifying, subfamily J, member 8 opener |
Direct Interaction | yes |
KCNJ8 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
3764 | Entrez Gene ID |
Initial Gene Query | Kir6.1 |
Counted Citations from 1950-2000 | 247 |
ION CHANNEL |
KCNJ8 | Display Id |
ENSG00000121361 | Ensembl Gene Id |
ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8 (POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 8) (INWARDLY RECTIFIER K(+) CHANNEL KIR6.1) (UKATP-1). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15842] | Description |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
KCNJ8 | Gene Symbol |
Target Class | Transporters |
Target Subclass | TC:1.A.2.1 |
ENSG00000121361 | Ensembl Gene Id |
Q15842 | Uniprot Accession |
KCNJ8 | Gene Symbol |
Target Main Class | Transporters |
Target Subclass | InwardlyRectifyingKchannel |
Target Subclass | Channels |
KCNJ8 | GENE_SYMBOL |
ATP-sensitive inward rectifier potassium channel 8 | UNIPROT |
Inward rectifier K(+) channel Kir6.1 | UNIPROT |
ENSG00000121361 | Gene Symbol |
KCNJ8 | Ensembl Id |
DRUGGABLE GENOME |
ATP-sensitive inward rectifier potassium channel 8 | Gene Name |
Q15842 | UniProt ID |
ION CHANNEL |