• LTB 4050 Druggable Genome

    Alternate Names:

    4050
    LYMPHOTOXIN BETA
    LTB
    TNFC
    TNFSF3
    TNLG1C
    p33
    600978
    6711
    ENSG00000227507
    OTTHUMG00000031136
    PA30475
    TNF-C
    Tumor necrosis factor ligand superfamily member 3
    Tumor necrosis factor C
    Lymphotoxin-beta
    LT-beta
    Q06643

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Ligand
    Target Subclass Cytokine
    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 15.46

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Heterotrimeric lymphotoxin LTa1b2 inhibitor
    Direct Interaction yes
    Trial Name baminercept, BG-9924

    PMIDs:
    None found


  • Interaction Score: 2.81

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

    • Version: 101_38

    Alternate Names:
    LTB Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    LTB Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Ligand
    Target Subclass Cytokine

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000227507 Gene Symbol
    LTB Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    TNFSF3 GENE_SYMBOL
    LTB GENE_SYMBOL
    Lymphotoxin-beta UNIPROT

    Gene Info:

    Publications:

    • Version: 18-August-2020

    Alternate Names:
    PA30475 PharmGKB ID

    Gene Info:

    Publications: