MELK Gene Record

  • MELK 9833 Druggable Genome

    Alternate Names:

    9833
    MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
    MELK
    HPK38
    607025
    16870
    ENSG00000165304
    OTTHUMG00000019906
    Q14680
    MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (EC 2.7.1.37) (HMELK) (PROTEIN KINASE PK38) (HPK38). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14680]
    MELK_HUMAN
    KIAA0175
    Tyrosine-protein kinase MELK
    T61518
    T96892

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Human Readable Name KINASE
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • BMS-387032   MELK

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MLN-8054   MELK

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL406845   MELK

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SB-220025   MELK

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AST-487   MELK

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GW843682X   MELK

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SNS-314   MELK

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • JNJ-7706621   MELK

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LINIFANIB   MELK

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   MELK

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   MELK

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   MELK

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   MELK

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   MELK

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   MELK

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   MELK

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   MELK

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000165304

    • Version: 101_38

    Alternate Names:
    MELK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000165304

    • Version: 26-July-2011

    Alternate Names:
    MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (EC 2.7.1.37) (HMELK) (PROTEIN KINASE PK38) (HPK38). [SOURCE:UNIPROT/SWISSPROT;ACC:Q14680] Description
    ENSG00000165304 Ensembl Gene Id
    MELK Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q14680

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000165304 Ensembl Gene Id
    9833 Entrez Gene Id
    Q14680 Uniprot Accession

    Gene Info:
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000165304

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000165304 Gene Symbol
    MELK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: MELK

    • Version: 19.3

    Alternate Names:
    ENSG00000165304 Ensembl Gene ID
    KIAA0175 Human Protein Atlas Gene Synonym
    Maternal embryonic leucine zipper kinase Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: MELK

    • Version: 01-February-2022

    Alternate Names:
    KIAA0175 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: MELK

    • Version: 27-Jun-2013

    Alternate Names:
    9833 Gene ID
    HPK38 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Maternal embryonic leucine zipper kinase

    • Version: 2020.06.01

    Alternate Names:
    MELK TTD Gene Abbreviation
    T96892 TTD Target ID

    Gene Info:

    Publications:

  • TTD: Tyrosine-protein kinase MELK

    • Version: 2020.06.01

    Alternate Names:
    MELK TTD Gene Abbreviation
    T61518 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: MELK

    • Version: 01-February-2022

    Alternate Names:
    Maternal embryonic leucine zipper kinase Gene Name
    Q14680 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: MELK

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: