P4HB Gene Record

  • P4HB 5034 Druggable Genome

    Alternate Names:

    5034
    PROLYL 4-HYDROXYLASE SUBUNIT BETA
    P4HB
    CLCRP1
    DSI
    ERBA2L
    GIT
    P4Hbeta
    PDI
    PDIA1
    PHDB
    PO4DB
    PO4HB
    PROHB
    176790
    8548
    ENSG00000185624
    OTTHUMG00000150269
    P07237
    PDIA1_HUMAN
    PROTEIN DISULFIDE-ISOMERASE
    p55
    Cellular thyroid hormone-binding protein
    PROTEIN DISULFIDE-ISOMERASE PRECURSOR (EC 5.3.4.1) (PDI) (PROLYL 4- HYDROXYLASE BETA SUBUNIT) (CELLULAR THYROID HORMONE BINDING PROTEIN) (P55). [SOURCE:UNIPROT/SWISSPROT;ACC:P07237]

    Gene Info:

    Interpro Name Thioredoxin domain
    Interpro Acc IPR013766
    Interpro Type Domain
    Interpro Short Name Thioredoxin_domain
    Human Readable Name THIOREDOXIN
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    EXTERNAL SIDE OF PLASMA MEMBRANE
    DRUGGABLE GENOME
    THIOREDOXIN
    ENZYME

    Publications:

  • LIQUIRITIN   P4HB

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ASTRAGALIN   P4HB

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL579956   P4HB

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LOMITAPIDE MESYLATE   P4HB

    Interaction Score: 3.43

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Microsomal triglyceride transfer protein inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • QUERCITRIN   P4HB

    Interaction Score: 2.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DIHYDRODAPHNODORIN B   P4HB

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SYROSINGOPINE   P4HB

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL522983   P4HB

    Interaction Score: 0.62

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RALOXIFENE HYDROCHLORIDE   P4HB

    Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000185624

    • Version: 101_38

    Alternate Names:
    P4HB Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000185624

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000185624 Ensembl Gene Id
    PROTEIN DISULFIDE-ISOMERASE PRECURSOR (EC 5.3.4.1) (PDI) (PROLYL 4- HYDROXYLASE BETA SUBUNIT) (CELLULAR THYROID HORMONE BINDING PROTEIN) (P55). [SOURCE:UNIPROT/SWISSPROT;ACC:P07237] Description
    P4HB Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: P07237

    • Version: 11-September-2012

    Alternate Names:
    P4HB Uniprot Gene Name
    ENSG00000185624 Ensembl Gene Id
    P07237 Uniprot Accession

    Gene Info:
    Interpro Name Thioredoxin domain
    Interpro Acc IPR013766
    Interpro Type Domain

    Gene Categories:
    DRUGGABLE GENOME, THIOREDOXIN

    Publications:

  • HingoraniCasas: ENSG00000185624

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000185624 Gene Symbol
    P4HB Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: ERBA2L

    • Version: chembl_23

    Alternate Names:
    PDI GENE_SYMBOL
    PDIA1 GENE_SYMBOL
    PO4DB GENE_SYMBOL

    Gene Info:

    Publications:

  • HumanProteinAtlas: P4HB

    • Version: 19.3

    Alternate Names:
    ENSG00000185624 Ensembl Gene ID
    DSI Human Protein Atlas Gene Synonym
    ERBA2L Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: P4HB

    • Version: 01-February-2022

    Alternate Names:
    ERBA2L GO Gene Synonym
    PDI GO Gene Synonym
    PDIA1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    EXTERNAL SIDE OF PLASMA MEMBRANE

    Publications:

  • Pharos: P4HB

    • Version: 01-February-2022

    Alternate Names:
    Protein disulfide-isomerase Gene Name
    P07237 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • DTC: P4HB

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: