PAK1 Gene Record

  • PAK1 5058 Druggable GenomeClinically Actionable

    Alternate Names:

    5058
    P21 (RAC1) ACTIVATED KINASE 1
    PAK1
    PAKalpha
    602590
    8590
    ENSG00000149269
    OTTHUMG00000165138
    Q13153
    SERINE/THREONINE-PROTEIN KINASE PAK 1
    PAK1_HUMAN
    SERINE/THREONINE-PROTEIN KINASE PAK 1 (EC 2.7.1.37) (P21-ACTIVATED KINASE 1) (PAK-1) (P65-PAK) (ALPHA-PAK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13153]
    IDDMSSD
    alpha-PAK
    p65-PAK

    Gene Info:

    Interpro Acc IPR002290
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

  • AZD-1152-HQPA   PAK1

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MLN-8054   PAK1

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LAUROGUADINE   PAK1

    Interaction Score: 0.22

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   PAK1

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   PAK1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   PAK1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   PAK1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   PAK1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   PAK1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   PAK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000149269

    • Version: 101_38

    Alternate Names:
    PAK1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000149269

    • Version: 26-July-2011

    Alternate Names:
    SERINE/THREONINE-PROTEIN KINASE PAK 1 (EC 2.7.1.37) (P21-ACTIVATED KINASE 1) (PAK-1) (P65-PAK) (ALPHA-PAK). [SOURCE:UNIPROT/SWISSPROT;ACC:Q13153] Description
    ENSG00000149269 Ensembl Gene Id
    PAK1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q13153

    • Version: 11-September-2012

    Alternate Names:
    SERINE/THREONINE-PROTEIN KINASE PAK 1 Uniprot Protein Name
    PAK1_HUMAN Uniprot Id
    Q13153 Uniprot Accession

    Gene Info:
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000149269

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000149269 Gene Symbol
    PAK1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Tempus: PAK1

    • Version: 11-November-2018

    Alternate Names:
    PAK1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • dGene: PAK1

    • Version: 27-Jun-2013

    Alternate Names:
    5058 Gene ID
    PAKalpha dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Pharos: PAK1

    • Version: 01-February-2022

    Alternate Names:
    Serine/threonine-protein kinase PAK 1 Gene Name
    Q13153 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications:

  • MskImpact: PAK1

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • DTC: PAK1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • GO: PAK1

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications: