PAK4 Gene Record

  • PAK4 10298 Druggable Genome

    Alternate Names:

    10298
    P21 (RAC1) ACTIVATED KINASE 4
    PAK4
    605451
    16059
    ENSG00000130669
    OTTHUMG00000182800
    O96013
    KIAA1142
    Serine/threonine-protein kinase PAK 4
    p21-activated kinase 4
    PAK-4
    SERINE/THREONINE-PROTEIN KINASE PAK 4 (EC 2.7.1.37) (P21-ACTIVATED KINASE 4) (PAK-4). [SOURCE:UNIPROT/SWISSPROT;ACC:O96013]
    PAK4_HUMAN
    PAK-4 protein kinase
    T98293
    -

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Interpro Type Domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

  • PF-03758309   PAK4

    Interaction Score: 6.87

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serine/threonine-protein kinase PAK 4 inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions TTD

  • KPT-9274   PAK4

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • ADAVOSERTIB   PAK4

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   PAK4

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GO-6976   PAK4

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   PAK4

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PALBOCICLIB   PAK4

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • JNJ-7706621   PAK4

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALSTERPAULLONE   PAK4

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PD-0166285   PAK4

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   PAK4

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   PAK4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   PAK4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   PAK4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   PAK4

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   PAK4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   PAK4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   PAK4

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000130669

    • Version: 101_38

    Alternate Names:
    PAK4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O96013

    • Version: 11-September-2012

    Alternate Names:
    O96013 Uniprot Accession
    SERINE/THREONINE-PROTEIN KINASE PAK 4 Uniprot Protein Name
    PAK4 Uniprot Gene Name

    Gene Info:
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Human Readable Name KINASE

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000130669

    • Version: 26-July-2011

    Alternate Names:
    SERINE/THREONINE-PROTEIN KINASE PAK 4 (EC 2.7.1.37) (P21-ACTIVATED KINASE 4) (PAK-4). [SOURCE:UNIPROT/SWISSPROT;ACC:O96013] Description
    ENSG00000130669 Ensembl Gene Id
    PAK4 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000130669

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000130669 Gene Symbol
    PAK4 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: KIAA1142

    • Version: chembl_23

    Alternate Names:
    KIAA1142 GENE_SYMBOL
    PAK4 GENE_SYMBOL
    Serine/threonine-protein kinase PAK 4 UNIPROT

    Gene Info:

    Publications:

  • GO: PAK4

    • Version: 01-February-2022

    Alternate Names:
    KIAA1142 GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • dGene: PAK4

    • Version: 27-Jun-2013

    Alternate Names:
    10298 Gene ID
    - dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: PAK-4 protein kinase

    • Version: 2020.06.01

    Alternate Names:
    PAK4 TTD Gene Abbreviation
    T98293 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: PAK4

    • Version: 01-February-2022

    Alternate Names:
    Serine/threonine-protein kinase PAK 4 Gene Name
    O96013 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: PAK4

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: