DGIdb - PLCG1 Gene Record

PLCG1 5335 Druggable Genome

Alternate Names:

5335
PHOSPHOLIPASE C GAMMA 1
PLCG1
NCKAP3
PLC-II
PLC1
PLC148
PLCgamma1
172420
9065
ENSG00000124181
OTTHUMG00000033082
P19174
PLCG1_HUMAN
1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (EC 3.1.4.11) (PHOSPHOINOSITIDE PHOSPHOLIPASE C) (PLC-GAMMA-1) (PHOSPHOLIPASE C-GAMMA-1) (PLC-II) (PLC-148). [SOURCE:UNIPROT/SWISSPROT;ACC:P19174]
1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-1
PA33392

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Interpro Name	Phosphoinositide phospholipase C
Interpro Short Name	Pinositol_PLipase_C
Human Readable Name	PHOSPHOLIPASE
Uniprot Status	Swiss-Prot
Interpro Acc	IPR001192
Interpro Type	Family
Uniprot Evidence	1: Evidence at protein level
Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

KINASE
PHOSPHOLIPASE
DRUGGABLE GENOME

Publications:

Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics

PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER PLCG1

Interaction Score: 5.15

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DICLOFENAC PLCG1

Interaction Score: 0.98

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26398624

Sources:
PharmGKB
CEFIXIME PLCG1

Interaction Score: 0.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ACETAMINOPHEN PLCG1

Interaction Score: 0.53

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26398624

Sources:
PharmGKB
9,10-PHENANTHRENEQUINONE PLCG1

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ASPIRIN PLCG1

Interaction Score: 0.29

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
26398624

Sources:
PharmGKB

Ensembl: ENSG00000124181
- Version: 101_38
Alternate Names:

PLCG1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P19174
- Version: 11-September-2012
Alternate Names:

PLCG1 Uniprot Gene Name

PLCG1_HUMAN Uniprot Id

ENSG00000124181 Ensembl Gene Id

Gene Info:

Interpro Name Phosphoinositide phospholipase C

Interpro Short Name Pinositol_PLipase_C

Human Readable Name PHOSPHOLIPASE

Gene Categories:

PHOSPHOLIPASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000124181

Version: 26-July-2011

Alternate Names:

1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (EC 3.1.4.11) (PHOSPHOINOSITIDE PHOSPHOLIPASE C) (PLC-GAMMA-1) (PHOSPHOLIPASE C-GAMMA-1) (PLC-II) (PLC-148). [SOURCE:UNIPROT/SWISSPROT;ACC:P19174] Description

ENSG00000124181 Ensembl Gene Id

PLCG1 Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

PharmGKB: PLCG1
- Version: 18-August-2020
Alternate Names:

PA33392 PharmGKB ID

Gene Info:

Publications:

Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics
Pharos: PLCG1
- Version: 01-February-2022
Alternate Names:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Gene Name

P19174 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:
DTC: PLCG1
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

PLCG1	Uniprot Gene Name
PLCG1_HUMAN	Uniprot Id
ENSG00000124181	Ensembl Gene Id

1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (EC 3.1.4.11) (PHOSPHOINOSITIDE PHOSPHOLIPASE C) (PLC-GAMMA-1) (PHOSPHOLIPASE C-GAMMA-1) (PLC-II) (PLC-148). [SOURCE:UNIPROT/SWISSPROT;ACC:P19174]	Description
ENSG00000124181	Ensembl Gene Id
PLCG1	Display Id

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	Gene Name
P19174	UniProt ID

PLCG1 Gene Record

PLCG1 5335 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

DICLOFENAC PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26398624

Sources: PharmGKB

CEFIXIME PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

ACETAMINOPHEN PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26398624

Sources: PharmGKB

9,10-PHENANTHRENEQUINONE PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

ASPIRIN PLCG1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 26398624

Sources: PharmGKB

Ensembl: ENSG00000124181

Alternate Names: PLCG1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

HopkinsGroom: P19174

Alternate Names: PLCG1 Uniprot Gene Name PLCG1_HUMAN Uniprot Id ENSG00000124181 Ensembl Gene Id

Gene Info: Interpro Name Phosphoinositide phospholipase C Interpro Short Name Pinositol_PLipase_C Human Readable Name PHOSPHOLIPASE

Gene Categories: PHOSPHOLIPASE, DRUGGABLE GENOME

Publications:

RussLampel: ENSG00000124181

Alternate Names: 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (EC 3.1.4.11) (PHOSPHOINOSITIDE PHOSPHOLIPASE C) (PLC-GAMMA-1) (PHOSPHOLIPASE C-GAMMA-1) (PLC-II) (PLC-148). [SOURCE:UNIPROT/SWISSPROT;ACC:P19174] Description ENSG00000124181 Ensembl Gene Id PLCG1 Display Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

PharmGKB: PLCG1

Alternate Names: PA33392 PharmGKB ID

Gene Info:

Publications: Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics

Pharos: PLCG1

Alternate Names: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Gene Name P19174 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

DTC: PLCG1

Alternate Names:

Gene Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
26398624

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
26398624

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
26398624

Sources:
PharmGKB

Alternate Names:

PLCG1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PLCG1 Uniprot Gene Name

PLCG1_HUMAN Uniprot Id

ENSG00000124181 Ensembl Gene Id

Gene Info:

Interpro Name Phosphoinositide phospholipase C

Interpro Short Name Pinositol_PLipase_C

Human Readable Name PHOSPHOLIPASE

Gene Categories:

PHOSPHOLIPASE, DRUGGABLE GENOME

Alternate Names:

1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA 1 (EC 3.1.4.11) (PHOSPHOINOSITIDE PHOSPHOLIPASE C) (PLC-GAMMA-1) (PHOSPHOLIPASE C-GAMMA-1) (PLC-II) (PLC-148). [SOURCE:UNIPROT/SWISSPROT;ACC:P19174] Description

ENSG00000124181 Ensembl Gene Id

PLCG1 Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

PA33392 PharmGKB ID

Publications:

Ayuso P et al., 2015, Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients., Pharmacogenet Genomics

Alternate Names:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Gene Name

P19174 UniProt ID

Gene Categories:

KINASE